Blanc A, Delfraro A, Frabasile S, Arbiza J
Sección Virología, Facultad de Ciencias-Universidad de la República, Iguá, Montevideo, Uruguay.
Arch Virol. 2005 Mar;150(3):603-9. doi: 10.1007/s00705-004-0412-x. Epub 2004 Oct 11.
Genotypes of Human respiratory syncytial virus (HRSV) of group B from Uruguay were assigned to strains isolated during 1999 and 2001 outbreaks and others formerly reported isolated in the period 1989-1996. The nucleotide sequences of the C-terminal portion of the G protein were compared to sequences representative of previously defined HRSV genotypes. Most Uruguayan strains clustered into five of the previously identified genotypes. Nine isolates clustered in two genotypes named URU1 and URU2 which were not described up to present. Two of the analyzed sequences isolated in 2001 have a six nucleotide duplication that is discussed in terms of HRSV variability.
对来自乌拉圭的B组人呼吸道合胞病毒（HRSV）基因型进行了分类，这些基因型来自1999年和2001年疫情期间分离出的毒株以及之前报道的1989 - 1996年期间分离出的毒株。将G蛋白C端部分的核苷酸序列与先前定义的HRSV基因型的代表性序列进行了比较。大多数乌拉圭毒株聚集在先前确定的五个基因型中。九个分离株聚集在两个名为URU1和URU2的基因型中，这两个基因型此前尚未被描述。2001年分离出的两个分析序列有一个六核苷酸重复，本文从HRSV变异性的角度对此进行了讨论。
