La Vu Dang, Clavel Benoît, Lepetz Sébastien, Aboudharam Gérard, Raoult Didier, Drancourt Michel
Unité des Rickettsies, Faculté de Medecine, Université de la Méditerranée, Marseille, France.
Clin Infect Dis. 2004 Nov 1;39(9):1391-4. doi: 10.1086/424884. Epub 2004 Oct 12.
Bartonella species are responsible for chronic bacteremia in domestic cats, which raises a question about the antiquity of the relationship between Bartonella species and cats that act as reservoirs for the organism. The sequencing of Bartonella pap31 and groEL genes from the dental pulp of cats dating from the 13th to 16th centuries identified the presence of B. henselae genotype Houston; the observation of a unique mutation in the results of PCR assays for Bartonella species ruled out modern DNA contamination of the dental pulp samples. We conclude that cats had bacteremia due to B. henselae 800 years ago.
巴尔通体属细菌可导致家猫出现慢性菌血症，这引发了一个问题，即巴尔通体属细菌与作为该病原体宿主的猫之间的关系究竟起源于何时。对13至16世纪猫牙髓中的巴尔通体pap31和groEL基因进行测序，确定存在亨氏巴尔通体休斯顿基因型；在针对巴尔通体属细菌的聚合酶链反应检测结果中观察到一个独特的突变，排除了牙髓样本受到现代DNA污染的可能性。我们得出结论，800年前猫就因亨氏巴尔通体而出现菌血症。
Zotero 插件