Sternfeld Barbara, Wang Hua, Quesenberry Charles P, Abrams Barbara, Everson-Rose Susan A, Greendale Gail A, Matthews Karen A, Torrens Javier I, Sowers MaryFran
Division of Research, Kaiser Permanente, Oakland, CA 94611, USA.
Am J Epidemiol. 2004 Nov 1;160(9):912-22. doi: 10.1093/aje/kwh299.
Controversy exists regarding the extent to which age, menopausal status, and/or lifestyle behaviors account for the increased weight, fat mass, and central adiposity experienced by midlife women. To address this question, the authors longitudinally examined the relations of aging, menopausal status, and physical activity to weight and waist circumference in 3,064 racially/ethnically diverse women aged 42-52 years at baseline who were participating in the Study of Women's Health Across the Nation (SWAN), an observational study of the menopausal transition. Over 3 years of follow-up (1996-1997 to 1999-2000), mean weight increased by 2.1 kg (standard deviation (SD), 4.8) or 3.0% (SD, 6.5) and mean waist circumference increased by 2.2 cm (SD, 5.4) or 2.8% (SD, 6.3). Change in menopausal status was not associated with weight gain or significantly associated with increases in waist circumference. A one-unit increase in reported level of sports/exercise (on a scale of 1-5) was longitudinally related to decreases of 0.32 kg in weight (p < 0.0001) and 0.10 cm in waist circumference (not significant). Similar inverse relations were observed for daily routine physical activity (biking and walking for transportation and less television viewing). These findings suggest that, although midlife women tend to experience increases in weight and waist circumference over time, maintaining or increasing participation in regular physical activity contributes to prevention or attenuation of those gains.
关于年龄、绝经状态和/或生活方式行为在多大程度上导致中年女性体重增加、脂肪量增加和中心性肥胖,目前存在争议。为了解决这个问题,作者对3064名年龄在42 - 52岁、种族/民族各异的女性进行了纵向研究,这些女性在基线时参加了全国女性健康研究(SWAN),这是一项关于绝经过渡的观察性研究,研究衰老、绝经状态和身体活动与体重和腰围的关系。在3年的随访期(1996 - 1997年至1999 - 2000年)内,平均体重增加了2.1千克(标准差(SD),4.8),即增加了3.0%(SD,6.5),平均腰围增加了2.2厘米(SD,5.4),即增加了2.8%(SD,6.3)。绝经状态的变化与体重增加无关,与腰围增加也无显著关联。报告的体育锻炼水平(1 - 5级)每增加一个单位,体重纵向减少0.32千克(p < 0.0001),腰围减少0.10厘米(不显著)。日常身体活动(骑自行车和步行出行以及减少看电视时间)也观察到类似的反向关系。这些发现表明,尽管中年女性体重和腰围往往会随时间增加,但保持或增加规律的身体活动有助于预防或减轻这些增加。