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波纳雷酰胺A - C,从海洋海绵Axinyssa aplysinoides中分离出的新型倍半萜类化合物。

Boneratamides A-C, new sesquiterpenoids isolated from the marine sponge Axinyssa aplysinoides.

作者信息

Williams David E, Patrick Brian O, Tahir Akbar, Van Soest Rob, Roberge Michel, Andersen Raymond J

机构信息

Department of Chemistry, Earth & Ocean Sciences, University of British Columbia, Vancouver, Canada, V6T 1Z1.

出版信息

J Nat Prod. 2004 Oct;67(10):1752-4. doi: 10.1021/np049798g.

Abstract

Three new sesquiterpenoids, boneratamides A (1)-C (3), have been isolated as their methyl esters 4-6 from extracts of the marine sponge Axinyssa aplysinoides collected in Indonesia. The structures of methyl esters 4-6 were elucidated by analysis of spectroscopic data and confirmed by single-crystal X-ray diffraction analysis of 4.

摘要

从印度尼西亚采集的海洋海绵Axinyssa aplysinoides提取物中分离出三种新的倍半萜类化合物,即骨酰胺A(1)-C(3),其甲酯形式为4-6。通过光谱数据分析阐明了甲酯4-6的结构,并通过对4进行单晶X射线衍射分析加以证实。

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