Zillikens M C, van den Berg J W, Wilson J H, Swart G R
Department of Internal Medicine II, University Hospital, Rotterdam, The Netherlands.
Am J Clin Nutr. 1992 Mar;55(3):621-5. doi: 10.1093/ajcn/55.3.621.
Bioelectrical impedance analysis (BIA) is a simple technique for determining body water and calculating body composition. It has been validated in healthy control subjects but not in patients with liver disease. We examined the ability of BIA to detect changes in total body water (TBW) due to removal of ascites. In 12 cirrhotic patients, BIA of the whole body and of body segments was performed before and after treatment of ascites with paracentesis (n = 12) and diuretics (n = 2). TBW changes predicted by BIA, by using two prediction equations, were significantly less than body weight changes (51% and 45% of the weight loss). BIA of body segments showed highly significant changes in both the trunk and the leg and small changes in the arm. These data indicate that BIA of the whole body is not a suitable technique for monitoring fluid changes in cirrhotic patients with ascites. Changes in BIA of body segments may be due to mobilization of edema after the removal of ascites.
生物电阻抗分析（BIA）是一种用于测定身体水分和计算身体成分的简单技术。它已在健康对照受试者中得到验证，但尚未在肝病患者中得到验证。我们研究了BIA检测因腹水清除导致的全身水（TBW）变化的能力。对12例肝硬化患者进行了腹水穿刺治疗（n = 12）和利尿剂治疗（n = 2）前后的全身及身体各部位的BIA检测。使用两个预测方程，BIA预测的TBW变化显著小于体重变化（体重减轻的51%和45%）。身体各部位的BIA显示，躯干和腿部有高度显著变化，手臂变化较小。这些数据表明，全身BIA不是监测肝硬化腹水患者液体变化的合适技术。身体各部位BIA的变化可能是由于腹水清除后水肿的消退。
