Wölnerhanssen B K, Ackermann C, Guenin M O, Kern B, Tondelli P, von Flüe M, Peterli R
Allgemeinchirurgische Klinik, St. Claraspital Basel, .
Chirurg. 2005 Mar;76(3):263-9. doi: 10.1007/s00104-004-0928-3.
We studied developments in indication, operation time, conversion rate, morbidity, and mortality from the beginning of laparoscopic cholecystectomy. Between 1990 and 2002 we prospectively evaluated 4498 patients undergoing cholecystectomy (CE), of whom 79% were treated laparoscopically (lap). In 6.6%, the procedure had to be converted from laparoscopic to open cholecystectomy (con), and 14% were performed open from the beginning (open). During the above time period, the rate of open CE decreased steadily (49% in 1990 to 7.2% in 2002). The average operation time of lap CE remained constant with an average of 74 min (range 20-330). The conversion rate decreased in spite of broader indication for lap CE in even more complicated gallstone diseases, from an initial 9.4% to 2.5%. Among intraoperative complications in lap and con, bile duct lesions remained constant with 5/3856 (0.1%), bleeding which led to conversion decreased from 1.9% to 0.3%, and the rate of gall bladder perforation increased from 12% to 20.5%. Thirty-day morbidity was 2% in lap CE, 5% in con, and 11.5% in open. The mortality was 0% in lap, 0.7% in con, and 1% in open.
Since the introduction of laparoscopic cholecystectomy the indication for this minimal-invasive operation steadily increased, the conversion-rate decreased and the complication-rate could be held low. Even with fast laparoscopic experience 7% of all cholecystectomies are technically difficult and remain to be carried out primarily in an open technique. The laparoscopic cholecystectomy has become the gold standard in the therapy of gallstone disease.
我们研究了自腹腔镜胆囊切除术开展以来在适应证、手术时间、中转率、发病率和死亡率方面的发展情况。1990年至2002年期间,我们对4498例行胆囊切除术(CE)的患者进行了前瞻性评估,其中79%接受了腹腔镜手术(lap)。6.6%的手术不得不从腹腔镜转换为开腹胆囊切除术(con),14%一开始就采用开腹手术(open)。在上述时间段内,开腹CE的比例稳步下降(1990年为49%,2002年为7.2%)。lap CE的平均手术时间保持恒定,平均为74分钟(范围20 - 330分钟)。尽管lap CE在更复杂的胆结石疾病中的适应证有所扩大,但中转率仍从最初的9.4%降至2.5%。在lap和con的术中并发症中,胆管损伤保持恒定,为5/3856(0.1%),导致中转的出血从1.9%降至0.3%,胆囊穿孔率从12%升至20.5%。lap CE的30天发病率为2%,con为5%,open为11.5%。lap的死亡率为0%,con为0.7%,open为1%。
自腹腔镜胆囊切除术引入以来,这种微创手术的适应证稳步增加,中转率降低,并发症发生率可保持在较低水平。即使有快速的腹腔镜手术经验,所有胆囊切除术中仍有7%在技术上具有挑战性,仍需主要采用开腹技术进行。腹腔镜胆囊切除术已成为胆结石疾病治疗的金标准。