Tong Louis, Saw Seang-Mei, Lin Yu, Chia Kee-Seng, Koh David, Tan Donald
Singapore National Eye Center, National University of Singapore.
Invest Ophthalmol Vis Sci. 2004 Nov;45(11):3914-8. doi: 10.1167/iovs.04-0492.
This study investigated the incidence and progression, as well as factors associated with changes in astigmatism in school children.
This was a prospective cohort study. Children 7 to 9 years of age, of Chinese, Malay, and Asian Indian ethnicity, were examined annually over a 4-year period. Cycloplegic autorefraction was performed. A questionnaire was used to evaluate risk factors for incidence and progression of astigmatism.
The cumulative 3-year incidence rate of astigmatism was 33.6% (cylinder power of 0.5 D or worse) or 11.5% (cylinder power of 1.0 D or worse). Myopic children had a higher incidence rate of astigmatism than nonmyopes (P <0.001). The mean J0 change per year was 0.012 D (95% CI: 0.007-0.018), whereas J45 did not show a significant change each year (mean, 0.001 D per year). Chinese children had greater worsening of J0 per year (P <0.001). Girls also had significantly greater progression of J0 than did boys (P <0.001). Similarly, myopia at baseline (P <0.001) and the hours of computer use (P=0.049) were associated with a greater progression rate of J0. J0 tended to improve in children with compound hyperopic astigmatism, worsen in children with compound myopic astigmatism, and remain stable in mixed astigmatics.
Although there was minimal progression of astigmatism in school age children (0.44-0.53 D) over this period of follow-up, incident cases of astigmatism (>1.0 D) were not uncommon. The progression rate of astigmatism was affected by the ethnicity, presence of myopia, axis, and subtype of astigmatism.
本研究调查了学龄儿童散光的发病率、进展情况以及与散光变化相关的因素。
这是一项前瞻性队列研究。对7至9岁的华裔、马来裔和印度裔儿童进行了为期4年的年度检查。进行了睫状肌麻痹验光。使用问卷评估散光发生和进展的危险因素。
散光的3年累积发病率为33.6%(柱镜度数为0.5 D或更差)或11.5%(柱镜度数为1.0 D或更差)。近视儿童的散光发病率高于非近视儿童(P<0.001)。每年J0的平均变化为0.012 D(95%CI:0.007 - 0.018),而J45每年没有显著变化(平均每年0.001 D)。华裔儿童每年J0的恶化程度更大(P<0.001)。女孩J0的进展也明显大于男孩(P<0.001)。同样,基线近视(P<0.001)和电脑使用时间(P = 0.049)与J0的更大进展率相关。复合远视散光儿童的J0倾向于改善,复合近视散光儿童的J0倾向于恶化,混合散光儿童的J0保持稳定。
尽管在这段随访期间学龄儿童散光的进展极小(0.44 - 0.53 D),但散光的新发病例(>1.0 D)并不少见。散光的进展率受种族、近视情况、轴位和散光亚型的影响。