Nkhoma Ella T, Ed Hsu Chiehwen, Hunt Victoria I, Harris Ann Marie
Department of Epidemiology, University of North Carolina at Chapel Hill, CB#7435, 2106-B McGavran-Greenberg Hall, Chapel Hill, NC 27599–7435, USA.
Int J Health Geogr. 2004 Oct 27;3(1):25. doi: 10.1186/1476-072X-3-25.
Accidental poisoning is one of the leading causes of injury in the United States, second only to motor vehicle accidents. According to the Centers for Disease Control and Prevention, the rates of accidental poisoning mortality have been increasing in the past fourteen years nationally. In Texas, mortality rates from accidental poisoning have mirrored national trends, increasing linearly from 1981 to 2001. The purpose of this study was to determine if there are spatiotemporal clusters of accidental poisoning mortality among Texas counties, and if so, whether there are variations in clustering and risk according to gender and race/ethnicity. The Spatial Scan Statistic in combination with GIS software was used to identify potential clusters between 1980 and 2001 among Texas counties, and Poisson regression was used to evaluate risk differences. RESULTS: Several significant (p < 0.05) accidental poisoning mortality clusters were identified in different regions of Texas. The geographic and temporal persistence of clusters was found to vary by racial group, gender, and race/gender combinations, and most of the clusters persisted into the present decade. Poisson regression revealed significant differences in risk according to race and gender. The Black population was found to be at greatest risk of accidental poisoning mortality relative to other race/ethnic groups (Relative Risk (RR) = 1.25, 95% Confidence Interval (CI) = 1.24 - 1.27), and the male population was found to be at elevated risk (RR = 2.47, 95% CI = 2.45 - 2.50) when the female population was used as a reference. CONCLUSION: The findings of the present study provide evidence for the existence of accidental poisoning mortality clusters in Texas, demonstrate the persistence of these clusters into the present decade, and show the spatiotemporal variations in risk and clustering of accidental poisoning deaths by gender and race/ethnicity. By quantifying disparities in accidental poisoning mortality by place, time and person, this study demonstrates the utility of the spatial scan statistic combined with GIS and regression methods in identifying priority areas for public health planning and resource allocation.
在美国,意外中毒是主要的伤害原因之一,仅次于机动车事故。根据疾病控制与预防中心的数据,在过去十四年里,全国意外中毒死亡率一直在上升。在得克萨斯州,意外中毒死亡率呈现出与全国趋势一致的情况,从1981年到2001年呈线性增长。本研究的目的是确定得克萨斯州各县意外中毒死亡率是否存在时空聚集现象,如果存在,按性别和种族/族裔划分,聚集情况和风险是否存在差异。结合地理信息系统(GIS)软件使用空间扫描统计量来识别1980年至2001年期间得克萨斯州各县之间的潜在聚集区域,并使用泊松回归来评估风险差异。结果:在得克萨斯州的不同地区发现了几个显著(p < 0.05)的意外中毒死亡聚集区域。发现聚集区域的地理和时间持续性因种族、性别以及种族/性别组合而异,并且大多数聚集区域一直持续到当前十年。泊松回归显示,根据种族和性别,风险存在显著差异。相对于其他种族/族裔群体,黑人意外中毒死亡风险最高(相对风险(RR)= 1.25,95%置信区间(CI)= 1.24 - 1.27),以女性群体为参照时,男性群体风险升高(RR = 2.47,95% CI = 2.45 - 2.50)。结论:本研究结果为得克萨斯州存在意外中毒死亡聚集区域提供了证据,证明这些聚集区域一直持续到当前十年,并显示了按性别和种族/族裔划分的意外中毒死亡风险和聚集情况的时空差异。通过按地点、时间和人群量化意外中毒死亡率差异,本研究证明了空间扫描统计量结合GIS和回归方法在确定公共卫生规划和资源分配优先领域方面的效用。