Coop Christopher, England Ronald W, Quinn James M
Department of Internal Medicine, 5th Medical Group, Minot Air Force Base, Minot, North Dakota 58705, USA.
Allergy Asthma Proc. 2004 Jul-Aug;25(4):263-6.
Allergic bronchopulmonary aspergillosis (ABPA) is a noninvasive complex hypersensitivity reaction that occurs in immunocompetent patients with asthma. Aspergillus can invade and disseminate, but this more commonly occurs in severely immunocompromised patients receiving high-dose corticosteroids. We report the case of a 13-year-old immunocompetent male patient with moderate persistent asthma who appeared to have invasive pulmonary aspergillosis on radiographic studies. With further evaluation and workup, it was determined that the patient did not have invasive pulmonary aspergillosis, but that he met the diagnostic criteria for ABPA. Although initially there was a deceptive invasive appearance, proper identification of ABPA facilitated selection of corticosteroid treatment that resulted in prompt clearing of the concerning infiltrates.
变应性支气管肺曲霉病（ABPA）是一种发生于免疫功能正常的哮喘患者的非侵袭性复杂超敏反应。曲霉能够侵袭和播散，但这种情况更常见于接受大剂量糖皮质激素治疗的严重免疫功能低下患者。我们报告一例13岁免疫功能正常的男性中度持续性哮喘患者，其影像学检查显示疑似侵袭性肺曲霉病。经过进一步评估和检查，确定该患者并无侵袭性肺曲霉病，但符合ABPA的诊断标准。尽管最初有类似侵袭性病变的假象，但正确识别ABPA有助于选择糖皮质激素治疗，从而使相关浸润影迅速消散。
