Marcq M, Germaud P, Cellerin L, Sagan C, Chailleux E
Service de Pneumologie, Hôpital G. & R. Laennec, CHU de Nantes, France.
Rev Mal Respir. 2004 Dec;21(6 Pt 1):1162-6. doi: 10.1016/s0761-8425(04)71593-4.
Respiratory aspergillosis with different physiopathologic mechanisms can be associated in one patient in rare occasions.
We review three cases associating an allergic bronchopulmonary aspergillosis (ABPA) and an other form of aspergillosis: aspergilloma, chronic necrotizing pulmonary aspergillosis and we present a review of literature.
Such associations result in diagnostic and therapeutic difficulties. Corticosteroid treatment used for ABPA can increase the risk of severe infections. Such cases are a good indication of systemic antifungal therapy.
具有不同病理生理机制的呼吸道曲霉病在罕见情况下可在同一患者中并存。
我们回顾了三例合并变应性支气管肺曲霉病(ABPA)和其他形式曲霉病(曲霉球、慢性坏死性肺曲霉病)的病例,并进行文献综述。
这种合并会导致诊断和治疗困难。用于ABPA的皮质类固醇治疗可增加严重感染的风险。此类病例是全身抗真菌治疗的良好指征。