Pavie Juliette, Lafaurie Matthieu, Lacroix Claire, Marie Zagdanski Anne, Debrosse Denis, Socié Gérard, Derouin Francis, Gluckman Eliane, Michel Molina Jean
Service des Maladies Infectieuses et Tropicales, Paris, France.
Scand J Infect Dis. 2004;36(10):767-9. doi: 10.1080/00365540410021081.
Mucormycosis is a rare, but severe, complication in allogenic bone-marrow recipients with a mortality rate of about 80%. Moreover, its incidence appears to have increased within the last decade. We report a case of pulmonary and nasal mucormycosis in a 55-y-old patient, which occurred 1 y after BMT. Treatment combining 4 months of amphotericin B, early surgical resection of infected tissue and discontinuation of immunosuppressive treatment allowed the cure of this mould infection.
毛霉菌病是异基因骨髓移植受者中一种罕见但严重的并发症，死亡率约为80%。此外，在过去十年中其发病率似乎有所上升。我们报告一例55岁患者发生的肺和鼻毛霉菌病，该病例在骨髓移植后1年出现。联合使用4个月的两性霉素B、早期手术切除感染组织以及停用免疫抑制治疗治愈了这种霉菌感染。
