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老年男性和女性的焦虑与死亡风险

Anxiety and the risk of death in older men and women.

作者信息

van Hout Hein P J, Beekman Aartjan T F, de Beurs Edwin, Comijs Hannie, van Marwijk Harm, de Haan Marten, van Tilburg Willem, Deeg Dorly J H

机构信息

Department of General Practice, Institute for Research in Extramural Medicine, VU University Medical Centre, Van der Boechorststraat 7,1081 BT Amsterdam, The Netherlands.

出版信息

Br J Psychiatry. 2004 Nov;185:399-404. doi: 10.1192/bjp.185.5.399.

DOI:10.1192/bjp.185.5.399
PMID:15516548
Abstract

BACKGROUND

There are inconsistent reports as to whether people with anxiety disorders have a higher mortality risk.

AIMS

To determine whether anxiety disorders predict mortality in older men and women in the community.

METHOD

Longitudinal data were used from a large, community-based random sample (n=3107) of older men and women (55-85 years) in The Netherlands, with a follow-up period of 7.5 years. Anxiety disorders were assessed according to DSM-III criteria in a two-stage screening design.

RESULTS

In men, the adjusted mortality risk was 1.78 (95% CI 1.01-3.13) in cases with diagnosed anxiety disorders at baseline. In women, no significant association was found with mortality.

CONCLUSIONS

The study revealed a gender difference in the association between anxiety and mortality. For men, but not for women, an increased mortality risk was found for anxiety disorders.

摘要

背景

关于焦虑症患者的死亡风险是否更高,存在相互矛盾的报道。

目的

确定焦虑症是否能预测社区中老年男性和女性的死亡率。

方法

使用来自荷兰一个大型社区随机样本(n = 3107)的55 - 85岁老年男性和女性的纵向数据,随访期为7.5年。在两阶段筛查设计中,根据《精神疾病诊断与统计手册》第三版标准评估焦虑症。

结果

在男性中,基线时被诊断为焦虑症的患者调整后的死亡风险为1.78(95%可信区间1.01 - 3.13)。在女性中,未发现与死亡率有显著关联。

结论

该研究揭示了焦虑与死亡率之间关联的性别差异。对于男性,而非女性,发现焦虑症会增加死亡风险。

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