前囊抛光对纤维化囊混浊的影响：三年结果
Effect of anterior capsule polishing on fibrotic capsule opacification: three-year results.
作者信息
Sacu Stefan, Menapace Rupert, Wirtitsch Matthias, Buehl Wolf, Rainer Georg, Findl Oliver
机构信息
Department of Ophthalmology, Medical University of Vienna, Medical School, Vienna, Austria.
出版信息
J Cataract Refract Surg. 2004 Nov;30(11):2322-7. doi: 10.1016/j.jcrs.2004.02.092.
PURPOSE
To evaluate the long-term effect of anterior capsule polishing on anterior capsule opacification (ACO) and peripheral fibrotic posterior capsule opacification (PCO).
SETTING
Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.
METHODS
This randomized double-blind study comprised 104 eyes of 52 patients with bilateral age-related cataract. All patients received round-edged intraocular lenses (IOLs); 26 received an SI-40 IOL (Advanced Medical Optics Inc.) in both eyes, and 26 received a Silens6 IOL (Domilens) in both eyes. Both IOLs consist of different silicone material and have different haptic angulation. The SI-40 IOL has 13.0 mm open-loop poly(methyl methacrylate) (PMMA) haptics angulated by 10 degrees. The Silens6 IOL has 12.5 mm open-loop PMMA haptics with no angulation. In 1 eye, the anterior capsule was extensively polished. The anterior capsule was left unpolished in the contralateral eye, which acted as a control. Digital slitlamp photographs of the ACO and fibrotic PCO were taken with a standardized technique for 3 years postoperatively. The intensity of ACO was measured objectively (score 0% to 100%) using Adobe Photoshop software. Fibrotic PCO was graded subjectively (score 0 to 4).
RESULTS
The mean ACO was 17% in the polished eyes and 26% in the control eyes (P = .0001). The mean fibrotic PCO score was 0.5 and 1.0, respectively (P = .0007). The mean ACO was 15% in the polished SI-40 eyes and 26% in the control SI-40 eyes (P = .01). It was 19% in the polished Silens6 eyes and 26% in the control Silens6 eyes (P = .003). The mean fibrotic PCO score was 0.4 in the polished SI-40 eyes and 1.1 in the control SI-40 eyes (P = .0006). It was 0.6 in the polished Silens6 eyes and 0.9 in the control Silens6 eyes (P = .08).
CONCLUSIONS
Three years after surgery, eyes in which the anterior capsule was extensively polished had less ACO and fibrotic PCO with both round-edged silicone IOLs. In eyes with Silens6 IOLs, however, the reduction in fibrotic PCO was not significant.
目的
评估前囊抛光对前囊混浊（ACO）和周边纤维化后囊混浊（PCO）的长期影响。
设置
奥地利维也纳医科大学眼科。
方法
这项随机双盲研究纳入了52例双侧年龄相关性白内障患者的104只眼。所有患者均植入了圆边人工晶状体（IOL）；26例患者双眼植入SI-40 IOL（Advanced Medical Optics Inc.），26例患者双眼植入Silens6 IOL（Domilens）。两种IOL由不同的硅酮材料制成，襻角不同。SI-40 IOL有13.0 mm开环聚甲基丙烯酸甲酯（PMMA）襻，襻角为10度。Silens6 IOL有12.5 mm开环PMMA襻，无襻角。一只眼中，前囊进行了广泛抛光。对侧眼的前囊未抛光，作为对照。术后3年采用标准化技术拍摄ACO和纤维化PCO的数字裂隙灯照片。使用Adobe Photoshop软件客观测量ACO的强度（评分0%至100%）。纤维化PCO进行主观分级（评分0至4）。
结果
抛光眼的平均ACO为17%，对照眼为26%（P = .0001）。纤维化PCO的平均评分分别为0.5和1.0（P = .0007）。抛光的SI-40眼的平均ACO为15%，对照的SI-40眼为26%（P = .01）。抛光的Silens6眼为19%，对照的Silens6眼为26%（P = .003）。抛光的SI-40眼的纤维化PCO平均评分为0.
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