Sacu Stefan, Menapace Rupert, Wirtitsch Matthias, Buehl Wolf, Rainer Georg, Findl Oliver
Department of Ophthalmology, Medical University of Vienna, Medical School, Vienna, Austria.
J Cataract Refract Surg. 2004 Nov;30(11):2322-7. doi: 10.1016/j.jcrs.2004.02.092.
To evaluate the long-term effect of anterior capsule polishing on anterior capsule opacification (ACO) and peripheral fibrotic posterior capsule opacification (PCO).
Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.
This randomized double-blind study comprised 104 eyes of 52 patients with bilateral age-related cataract. All patients received round-edged intraocular lenses (IOLs); 26 received an SI-40 IOL (Advanced Medical Optics Inc.) in both eyes, and 26 received a Silens6 IOL (Domilens) in both eyes. Both IOLs consist of different silicone material and have different haptic angulation. The SI-40 IOL has 13.0 mm open-loop poly(methyl methacrylate) (PMMA) haptics angulated by 10 degrees. The Silens6 IOL has 12.5 mm open-loop PMMA haptics with no angulation. In 1 eye, the anterior capsule was extensively polished. The anterior capsule was left unpolished in the contralateral eye, which acted as a control. Digital slitlamp photographs of the ACO and fibrotic PCO were taken with a standardized technique for 3 years postoperatively. The intensity of ACO was measured objectively (score 0% to 100%) using Adobe Photoshop software. Fibrotic PCO was graded subjectively (score 0 to 4).
The mean ACO was 17% in the polished eyes and 26% in the control eyes (P = .0001). The mean fibrotic PCO score was 0.5 and 1.0, respectively (P = .0007). The mean ACO was 15% in the polished SI-40 eyes and 26% in the control SI-40 eyes (P = .01). It was 19% in the polished Silens6 eyes and 26% in the control Silens6 eyes (P = .003). The mean fibrotic PCO score was 0.4 in the polished SI-40 eyes and 1.1 in the control SI-40 eyes (P = .0006). It was 0.6 in the polished Silens6 eyes and 0.9 in the control Silens6 eyes (P = .08).
Three years after surgery, eyes in which the anterior capsule was extensively polished had less ACO and fibrotic PCO with both round-edged silicone IOLs. In eyes with Silens6 IOLs, however, the reduction in fibrotic PCO was not significant.
评估前囊抛光对前囊混浊（ACO）和周边纤维化后囊混浊（PCO）的长期影响。
奥地利维也纳医科大学眼科。
这项随机双盲研究纳入了52例双侧年龄相关性白内障患者的104只眼。所有患者均植入了圆边人工晶状体（IOL）；26例患者双眼植入SI-40 IOL（Advanced Medical Optics Inc.），26例患者双眼植入Silens6 IOL（Domilens）。两种IOL由不同的硅酮材料制成，襻角不同。SI-40 IOL有13.0 mm开环聚甲基丙烯酸甲酯（PMMA）襻，襻角为10度。Silens6 IOL有12.5 mm开环PMMA襻，无襻角。一只眼中，前囊进行了广泛抛光。对侧眼的前囊未抛光，作为对照。术后3年采用标准化技术拍摄ACO和纤维化PCO的数字裂隙灯照片。使用Adobe Photoshop软件客观测量ACO的强度（评分0%至100%）。纤维化PCO进行主观分级（评分0至4）。
抛光眼的平均ACO为17%，对照眼为26%（P = .0001）。纤维化PCO的平均评分分别为0.5和1.0（P = .0007）。抛光的SI-40眼的平均ACO为15%，对照的SI-40眼为26%（P = .01）。抛光的Silens6眼为19%，对照的Silens6眼为26%（P = .003）。抛光的SI-40眼的纤维化PCO平均评分为0.
