Brasil-Neto J P, Cohen L G, Panizza M, Nilsson J, Roth B J, Hallett M
Human Cortical Physiology Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892.
J Clin Neurophysiol. 1992 Jan;9(1):132-6.
We studied the effects of coil orientation, stimulus intensity, and shape of the induced current pulse on the amplitudes of motor evoked potentials in the left abductor pollicis brevis of 10 normal adults who had transcranial magnetic stimulation. The optimal direction of currents induced in the brain is approximately perpendicular to the central sulcus, flowing diagonally from back to front. The most effective coil orientation depends on the shape of the induced current pulse and, when the first and second phases of the pulse are of similar size, also on the intensity of stimulation. Optimal mapping of the human motor cortex with magnetic stimulation requires knowledge of the influences of all these factors.
我们研究了线圈方向、刺激强度以及感应电流脉冲形状对10名接受经颅磁刺激的正常成年人左侧拇短展肌运动诱发电位幅度的影响。大脑中感应电流的最佳方向大致垂直于中央沟，从后向前呈对角线流动。最有效的线圈方向取决于感应电流脉冲的形状，并且当脉冲的第一阶段和第二阶段大小相似时，还取决于刺激强度。用磁刺激对人类运动皮层进行最佳映射需要了解所有这些因素的影响。
