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胚胎死亡与人类胚胎干细胞的创建

Embryonic death and the creation of human embryonic stem cells.

作者信息

Landry Donald W, Zucker Howard A

机构信息

Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.

出版信息

J Clin Invest. 2004 Nov;114(9):1184-6. doi: 10.1172/JCI23065.

DOI:10.1172/JCI23065
PMID:15520846
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC524233/
Abstract

The creation of human embryonic stem cells through the destruction of a human embryo pits the value of a potential therapeutic tool against that of an early human life. This contest of values has resulted in a polarized debate that neglects areas of common interest and perspective. We suggest that a common ground for pursuing research on human embryonic stem cells can be found by reconsidering the death of the human embryo and by applying to this research the ethical norms of essential organ donation.

摘要

通过破坏人类胚胎来制造人类胚胎干细胞,将一种潜在治疗工具的价值与早期人类生命的价值对立起来。这种价值观的冲突导致了一场两极分化的辩论,忽视了共同关注和观点的领域。我们认为,通过重新审视人类胚胎的死亡,并将重要器官捐赠的伦理规范应用于这项研究,可以找到开展人类胚胎干细胞研究的共同基础。

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Embryonic death and the creation of human embryonic stem cells.胚胎死亡与人类胚胎干细胞的创建
J Clin Invest. 2004 Nov;114(9):1184-6. doi: 10.1172/JCI23065.
2
Embryonic stem cell research: a moral defense.胚胎干细胞研究:一种道德辩护。
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The anti-cloning conundrum.反克隆难题。
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The use of embryonic stem cells for therapeutic research (the August 2001 report).用于治疗性研究的胚胎干细胞(2001年8月报告)
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The Shortage of Malaysian Stem Cell Ethics in Mainstream Database: a Preliminary Study.马来西亚主流数据库中干细胞伦理的缺失:一项初步研究。
Asian Bioeth Rev. 2019 Nov 28;11(4):437-460. doi: 10.1007/s41649-019-00102-5. eCollection 2019 Dec.
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Human-animal chimeras: ethical issues about farming chimeric animals bearing human organs.人兽嵌合体:养殖携带人体器官的嵌合体动物的伦理问题。
Stem Cell Res Ther. 2016 Jun 29;7(1):87. doi: 10.1186/s13287-016-0345-9.
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Developmental potential of clinically discarded human embryos and associated chromosomal analysis.临床废弃人类胚胎的发育潜能及相关染色体分析
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Gene Transfection of Human Turbinate Mesenchymal Stromal Cells Derived from Human Inferior Turbinate Tissues.源自人下鼻甲组织的人鼻甲间充质基质细胞的基因转染
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Triploid and diploid embryonic stem cell lines derived from tripronuclear human zygotes.来源于三原核人类受精卵的三倍体和二倍体胚胎干细胞系。
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Derivation of two new human embryonic stem cell lines from nonviable human embryos.从不可存活的人类胚胎中衍生出的两个新的人类胚胎干细胞系。
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Cell Prolif. 2011 Apr;44 Suppl 1(Suppl 1):70-84. doi: 10.1111/j.1365-2184.2010.00723.x.

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