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[腕管综合征]

[Carpal tunnel syndrome].

作者信息

Pritsch Tamir, Rosenblatt Yishai, Carmel Avshalom

机构信息

Department of Orthopedic Surgery B, Tel Aviv Sourasky Medical Center, Israel.

出版信息

Harefuah. 2004 Oct;143(10):743-8, 765, 764.

Abstract

Carpal tunnel syndrome is the most common peripheral nerve compression syndrome. Compression of the median nerve in the carpal tunnel, disrupts the blood-nerve barrier causing edema, inflammation and fibrosis of its surrounding connective tissues. In the next stage of the syndrome there is a disruption of the myelin coverage of the nerve followed by damage to the axons. Most carpal tunnel syndromes are idiopathic. Other causes include intrinsic factors (which cause pressure within the tunnel), extrinsic factors (which cause pressure from outside the tunnel) and overuse/exertional factors. Patients usually report numbness and pain of the palmar aspect of their 1st, 2nd, 3rd and radial half of their 4th finger, night pain and gradual worsening of their symptoms. At a later stage, weakness and atrophy of the thenar muscles appears. The physical examination may show a decrease in sensibility, positive provocative tests and a decrease in thenar strength. The typical finding in the nerve conduction tests is a prolonged latency period. The conservative treatment for carpal tunnel syndrome includes ergonomic modifications, anti inflammatory medications and splintage and less frequently, special exercise and therapeutic ultrasound. The indications for operative treatment are failure of conservative treatment or severe carpal tunnel syndrome. The purpose of the operation is to relieve the pressure in the carpal tunnel by dissecting the transverse ligament. The operation can be done in an open approach, endoscopic approach or limited invasive approach.

摘要

腕管综合征是最常见的周围神经卡压综合征。腕管内正中神经受压会破坏血-神经屏障,导致其周围结缔组织出现水肿、炎症和纤维化。在该综合征的下一阶段,神经的髓鞘覆盖会遭到破坏,随后轴突也会受损。大多数腕管综合征是特发性的。其他病因包括内在因素(导致腕管内压力升高)、外在因素(导致来自腕管外部的压力)以及过度使用/用力因素。患者通常会诉说示指、中指、环指桡侧半掌面麻木和疼痛,夜间疼痛,症状逐渐加重。在后期,鱼际肌会出现无力和萎缩。体格检查可能显示感觉减退、激发试验阳性以及鱼际肌力量减弱。神经传导测试的典型表现是潜伏期延长。腕管综合征的保守治疗包括进行工效学调整、使用抗炎药物和夹板固定,较少情况下会采用特殊锻炼和治疗性超声。手术治疗的指征是保守治疗失败或严重的腕管综合征。手术目的是通过切开横韧带来减轻腕管内压力。手术可采用开放手术、内镜手术或有限切开手术的方式进行。

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