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西班牙儿童肺孢子菌感染的血清阳性率很高。

High seroprevalence of Pneumocystis infection in Spanish children.

作者信息

Respaldiza N, Medrano F J, Medrano A C, Varela J M, de la Horra C, Montes-Cano M, Ferrer S, Wichmann I, Gargallo-Viola D, Calderon E J

机构信息

Research Unit, Virgen del Rocio University Hospital, Seville, Spain.

出版信息

Clin Microbiol Infect. 2004 Nov;10(11):1029-31. doi: 10.1111/j.1469-0691.2004.00974.x.

Abstract

Pneumocystis infection occurs worldwide, and most individuals test seropositive for Pneumocystis early in childhood. Little is known about the epidemiology of this infection in western Europe. The seroprevalence of Pneumocystis infection in 233 Spanish children was determined in a community study by immunoblot analysis of sera. The overall seroprevalence was 73%, with an age-related increase from 52% at 6 years to 66% at 10 years and 80% at 13 years. The data indicated a high seroprevalence of Pneumocystis infection in healthy Spanish children, thereby demonstrating that this pathogen is widespread in southern Spain.

摘要

肺孢子菌感染在全球范围内均有发生,大多数人在儿童早期检测肺孢子菌血清呈阳性。关于西欧这种感染的流行病学情况知之甚少。在一项社区研究中,通过对血清进行免疫印迹分析,确定了233名西班牙儿童肺孢子菌感染的血清阳性率。总体血清阳性率为73%,随年龄增长而升高,6岁时为52%,10岁时为66%,13岁时为80%。数据表明健康西班牙儿童中肺孢子菌感染的血清阳性率很高,从而证明这种病原体在西班牙南部广泛存在。

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