银屑病患者生活质量的决定因素：一项来自美国人群的研究。
Determinants of quality of life in patients with psoriasis: a study from the US population.
作者信息
Gelfand Joel M, Feldman Steven R, Stern Robert S, Thomas John, Rolstad Tara, Margolis David J
机构信息
Department of Dermatology and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, USA.
出版信息
J Am Acad Dermatol. 2004 Nov;51(5):704-8. doi: 10.1016/j.jaad.2004.04.014.
BACKGROUND
Psoriasis is a common disease with substantial effects on quality of life. Few quality of life studies have been performed in psoriasis patients from the general US population.
OBJECTIVE
To describe the determinants of quality of life in psoriasis patients from the US population.
METHODS
Patients were randomly selected from the US population. Patients who identified themselves as having been diagnosed with psoriasis by a physician were invited to complete a more detailed survey about quality of life.
RESULTS
Two hundred sixty-six psoriasis patients from the US population completed the detailed survey. Body surface area showed the strongest association with decrements in quality of life (Spearman 0.50, P < .0001). Younger patients and female patients also had statistically significant reductions in quality of life. Increasing psoriasis severity was associated with seeking care from multiple physicians and having decrements in income.
CONCLUSION
Patients with more extensive skin involvement have greater reductions in quality of life. Female patients and young patients are affected to a greater extent.
背景
银屑病是一种对生活质量有重大影响的常见疾病。在美国普通人群的银屑病患者中，很少有关于生活质量的研究。
目的
描述美国人群中银屑病患者生活质量的决定因素。
方法
从美国人群中随机选取患者。自我认定曾被医生诊断为银屑病的患者被邀请完成一项关于生活质量的更详细调查。
结果
来自美国人群的266名银屑病患者完成了详细调查。体表面积与生活质量下降的关联最为显著（斯皮尔曼相关系数为0.50，P < .0001）。年轻患者和女性患者的生活质量在统计学上也有显著下降。银屑病严重程度增加与向多位医生寻求治疗以及收入减少有关。
结论
皮肤受累范围更广的患者生活质量下降幅度更大。女性患者和年轻患者受到的影响更大。
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