Ghezzi Gioele, Costanzo Antonio, Borroni Riccardo G
Humanitas University, 20072 Pieve Emanuele, MI, Italy.
Dermatology Unit, Humanitas Research Hospital-IRCCS, 20089 Rozzano, MI, Italy.
J Clin Med. 2024 Aug 7;13(16):4623. doi: 10.3390/jcm13164623.
The assessment of quality of life (QoL) in patients with psoriasis plays a crucial role in understanding the impact of the disease and evaluating treatment outcomes. We provide an overview of the key measures used to assess QoL in psoriasis patients, including both generic and psoriasis-specific instruments. The limitations and strengths of instruments such as the Dermatology Life Quality Index (DLQI), Skindex, and Psoriasis Disability Index (PDI) are discussed, highlighting their psychometric properties and areas for improvement. Furthermore, this review examines the potential of disease-specific QoL measures in providing greater sensitivity to disease-related burden and change compared to generic instruments. However, most of the available psoriasis-specific patient-reported outcome measures need further validation. We aim to provide valuable insights into the importance of using validated QoL measures in clinical practice and research, ultimately contributing to a more comprehensive assessment of the impact of psoriasis on patients' lives and enhancing the evaluation of treatment interventions.
对银屑病患者生活质量（QoL）的评估在理解疾病影响和评估治疗效果方面起着至关重要的作用。我们概述了用于评估银屑病患者生活质量的关键指标，包括通用指标和银屑病特异性指标。讨论了诸如皮肤病生活质量指数（DLQI）、皮肤指数（Skindex）和银屑病残疾指数（PDI）等指标的局限性和优势，突出了它们的心理测量特性和改进领域。此外，本综述探讨了疾病特异性生活质量指标相较于通用指标在对疾病相关负担和变化提供更高敏感性方面的潜力。然而，大多数现有的银屑病特异性患者报告结局指标需要进一步验证。我们旨在为在临床实践和研究中使用经过验证的生活质量指标的重要性提供有价值的见解，最终有助于更全面地评估银屑病对患者生活的影响，并加强对治疗干预措施的评估。
