Gueroui Zoher, Libchaber Albert
Center for Studies in Physics and Biology, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA.
Phys Rev Lett. 2004 Oct 15;93(16):166108. doi: 10.1103/PhysRevLett.93.166108.
We report the study of the quenching of quantum dots (CdSe) by gold nanoparticles at the single-molecule level. Double-stranded DNA is used as a rigid spacer to tune the distance between the two nanoparticles. The width of the fluorescent intensity distribution, monitored at different interparticle distances, reflects both the nanoparticle heterogeneity and the fluorescence intermittency of the quantum dot. The fluorescence distribution emitted by single CdSe nanocrystals can easily be distinguished from the fluorescence of partially quenched CdSe. Our results show that the distance-dependence quenching is compatible with a Förster-type process.
我们报道了在单分子水平上对金纳米颗粒猝灭量子点（CdSe）的研究。双链DNA被用作刚性间隔物来调节两个纳米颗粒之间的距离。在不同颗粒间距离下监测到的荧光强度分布宽度，既反映了纳米颗粒的异质性，也反映了量子点的荧光间歇性。单个CdSe纳米晶体发出的荧光分布很容易与部分猝灭的CdSe的荧光区分开来。我们的结果表明，距离依赖性猝灭与福斯特型过程相符。
