Zhang Guicheng, Spickett Jeffery, Rumchev Krassi, Lee Andy H, Stick Stephen
School of Public Health, Curtin University of Technology, GPO Box U1987, Perth, WA 6845, Australia.
Respir Res. 2004 Nov 4;5(1):19. doi: 10.1186/1465-9921-5-19.
The home is the predominant environment for exposure to many environmental irritants such as air pollutants and allergens. Exposure to common indoor irritants including volatile organic compounds, formaldehyde and nitrogen dioxide, may increase the risk of snoring for children. The aim of this study was to investigate domestic environmental factors associated with snoring in children.
A school-based respiratory survey was administered during March and April of 2002. Nine hundred and ninety six children from four primary schools within the Perth metropolitan area were recruited for the study. A sub-group of 88 children aged 4-6 years were further selected from this sample for domestic air pollutant assessment.
The prevalences of infrequent snoring and habitual snoring in primary school children were 24.9% and 15.2% respectively. Passive smoking was found to be a significant risk factor for habitual snoring (odds ratio (OR) = 1.77; 95% confidence interval (CI): 1.20-2.61), while having pets at home appeared to be protective against habitual snoring (OR = 0.58; 95% CI: 0.37-0.92). Domestic pollutant assessments showed that the prevalence of snoring was significantly associated with exposure to nitrogen dioxide during winter. Relative to the low exposure category (<30 microg/m3), the adjusted ORs of snoring by children with medium (30 - 60 microg/m3) and high exposures (> 60 microg/m3) to NO2 were 2.5 (95% CI: 0.7-8.7) and 4.5 (95% CI: 1.4-14.3) respectively. The corresponding linear dose-response trend was also significant (P = 0.011).
Snoring is common in primary school children. Domestic environments may play a significant role in the increased prevalence of snoring. Exposure to nitrogen dioxide in domestic environment is associated with snoring in children.
家庭是接触许多环境刺激物(如空气污染物和过敏原)的主要环境。接触常见的室内刺激物,包括挥发性有机化合物、甲醛和二氧化氮,可能会增加儿童打鼾的风险。本研究的目的是调查与儿童打鼾相关的家庭环境因素。
2002年3月和4月进行了一项基于学校的呼吸调查。从珀斯大都市区的四所小学招募了996名儿童参与该研究。从这个样本中进一步选取了88名4至6岁的儿童组成一个亚组,用于家庭空气污染物评估。
小学生偶尔打鼾和习惯性打鼾的患病率分别为24.9%和15.2%。发现被动吸烟是习惯性打鼾的一个重要危险因素(优势比(OR)=1.77;95%置信区间(CI):1.20 - 2.61),而家中养宠物似乎对习惯性打鼾有保护作用(OR = 0.58;95% CI:0.37 - 0.92)。家庭污染物评估显示,打鼾的患病率与冬季接触二氧化氮显著相关。相对于低暴露类别(<30微克/立方米),二氧化氮中度暴露(30 - 60微克/立方米)和高度暴露(>60微克/立方米)的儿童打鼾的调整后OR分别为2.5(95% CI:0.7 - 8.7)和4.5(95% CI:1.4 - 14.3)。相应的线性剂量反应趋势也很显著(P = 0.011)。
打鼾在小学生中很常见。家庭环境可能在打鼾患病率增加中起重要作用。家庭环境中接触二氧化氮与儿童打鼾有关。