移植物抗宿主病患者尿液样本中高BK病毒载量与造血干细胞移植后出血性膀胱炎发生之间的关联。
Association between a high BK virus load in urine samples of patients with graft-versus-host disease and development of hemorrhagic cystitis after hematopoietic stem cell transplantation.
作者信息
Bogdanovic G, Priftakis P, Giraud G, Kuzniar M, Ferraldeschi R, Kokhaei P, Mellstedt H, Remberger M, Ljungman P, Winiarski J, Dalianis T
机构信息
Department of Oncology-Pathology, Karolinska Institute, Hudding University Hospital, Stockholm, Sweden.
出版信息
J Clin Microbiol. 2004 Nov;42(11):5394-6. doi: 10.1128/JCM.42.11.5394-5396.2004.
Abstract
BK virus (BKV) load in urine alone or in combination with acute graft-versus-host disease (GVHD) was correlated to development of hemorrhagic cystitis (HC). BKV load in combination with acute GVHD discriminated the best, while BKV and viral load alone, but not GVHD, still showed predictive ability for HC.
摘要
单独尿液中的BK病毒（BKV）载量或与急性移植物抗宿主病（GVHD）联合，均与出血性膀胱炎（HC）的发生相关。BKV载量与急性GVHD联合时鉴别能力最佳，而单独的BKV和病毒载量（而非GVHD）仍显示出对HC的预测能力。
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BK virus (BKV) quantification in urine samples of bone marrow transplanted patients is helpful for diagnosis of hemorrhagic cystitis, although wide individual variations exist.对骨髓移植患者尿液样本中的BK病毒（BKV）进行定量分析，有助于出血性膀胱炎的诊断，尽管个体差异很大。
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