Levin Frances Rudnick, Evans Suzette M, Vosburg Suzanne K, Horton Terry, Brooks Daniel, Ng Jennifer
Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, 1051 Riverside Drive Unit 66, New York City, NY 10032, USA.
Addict Behav. 2004 Dec;29(9):1875-82. doi: 10.1016/j.addbeh.2004.03.041.
Although there are some data suggesting that individuals with depressive disorders may be more likely to remain in treatment than those without depressive disorders, it is less clear how well other psychiatric subgroups compare to those without psychiatric comorbidity. This sample is a follow-up study of 135 individuals who were admitted into a therapeutic community. Individuals with attention-deficit hyperactivity disorder (ADHD), other Axis I disorders (no ADHD), and no Axis I disorders were compared. Although individuals with other Axis I disorders had a strikingly low early drop-out rate, after a prolonged time in treatment, the drop-out rate increased substantially, such that these individuals were found to complete treatment at a lower rate (17%) than those with no Axis I disorders (29%). Furthermore, individuals with ADHD were less likely to graduate treatment than those with other Axis I or no Axis I disorders (0%, 9%, and 19%, respectively). Future investigations may be useful to determine whether pharmacologic or nonpharmacologic interventions might improve treatment outcome.
尽管有一些数据表明，与没有抑郁症的人相比，患有抑郁症的人可能更有可能坚持治疗，但其他精神亚组与没有精神疾病合并症的人相比情况如何，尚不太清楚。该样本是对135名入住治疗社区的个体进行的随访研究。对患有注意力缺陷多动障碍（ADHD）、其他轴I障碍（无ADHD）和无轴I障碍的个体进行了比较。尽管患有其他轴I障碍的个体早期辍学率极低，但经过长时间治疗后，辍学率大幅上升，结果发现这些个体完成治疗的比例（17%）低于无轴I障碍的个体（29%）。此外，患有ADHD的个体比患有其他轴I障碍或无轴I障碍的个体毕业率更低（分别为0%、9%和19%）。未来的研究可能有助于确定药物或非药物干预是否可以改善治疗效果。
