Crabtree Valerie McLaughlin, Varni James W, Gozal David
Division of Pediatric Sleep Medicine and Kosair Children's Hospital Research Institute, Department of Pediatrics, University of Louisville School of Medicine, KY 40202, USA.
Sleep. 2004 Sep 15;27(6):1131-8. doi: 10.1093/sleep/27.6.1131.
Snoring and sleep-disordered breathing (SDB) are highly prevalent among children. The increasing trends of obesity in the pediatric population further predict an exacerbation of this public health problem. However, the impact of SDB on mood and quality of life and the confounder effect of obesity in this setting are unclear.
We studied a group of 85 clinically referred children, aged 8 to 12 years, with snoring and suspected SDB and 35 asymptomatic children (controls). All children completed validated questionnaires for the presence of depression (Children's Depression Inventory) and for health-related quality of life (PedsQL), and parents completed the Parent Report version of the PedsQL. Children referred to the Sleep Medicine Center for sleep-disordered breathing were further subdivided according to their body mass index > 95% for age and sex (n = 44) and with BMI < 95% for age and sex as ClinN1 (n = 41).
Parentally reported quality of life and physical health differed between obese and nonobese children. However, both groups with SDB had more-impaired quality of life and depressive symptoms than did controls.
Children with suspected SDB, regardless of the severity of apnea-hypopnea index or the presence of obesity, had more impairments in quality of life and depressive symptoms than did children who did not snore.
打鼾和睡眠呼吸紊乱（SDB）在儿童中非常普遍。儿科人群中肥胖率的上升进一步预示着这一公共卫生问题将加剧。然而，SDB对情绪和生活质量的影响以及肥胖在这种情况下的混杂效应尚不清楚。
我们研究了一组85名临床转诊的8至12岁打鼾且疑似患有SDB的儿童以及35名无症状儿童（对照组）。所有儿童都完成了关于是否存在抑郁（儿童抑郁量表）和与健康相关的生活质量（儿童生活质量量表）的有效问卷，家长完成了儿童生活质量量表家长报告版。因睡眠呼吸紊乱转诊至睡眠医学中心的儿童根据其年龄和性别的体重指数>95%（n = 44）以及年龄和性别的BMI<95%进一步细分为ClinN1（n = 41）。
家长报告的生活质量和身体健康在肥胖和非肥胖儿童之间存在差异。然而，两组患有SDB的儿童的生活质量受损程度和抑郁症状均比对照组更严重。
疑似患有SDB的儿童，无论呼吸暂停低通气指数的严重程度或是否存在肥胖，其生活质量受损程度和抑郁症状均比不打鼾的儿童更严重。
