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一项对固定局部义齿(FPDs)在至少5年观察期后的生存率和并发症发生率的系统评价。

A systematic review of the survival and complication rates of fixed partial dentures (FPDs) after an observation period of at least 5 years.

作者信息

Pjetursson Bjarni E, Tan Ken, Lang Niklaus P, Brägger Urs, Egger Matthias, Zwahlen Marcel

机构信息

School of Dental Medicine, University of Berne, Berne, Switzerland.

出版信息

Clin Oral Implants Res. 2004 Dec;15(6):625-42. doi: 10.1111/j.1600-0501.2004.01117.x.

Abstract

OBJECTIVES

The objective of this systematic review was to assess the 5- and 10-year survival of implant supported fixed partial dentures (FPDs) and to describe the incidence of biological and technical complications.

METHODS

An electronic MEDLINE search complemented by manual searching was conducted to identify prospective and retrospective cohort studies on FPDs with a mean follow-up time of at least 5 years. Patients had to have been examined clinically at the follow-up visit. Assessment of the identified studies and data abstraction was performed independently by two reviewers. Failure and complication rates were analyzed using random-effects Poisson regression models to obtain summary estimates of 5- and 10-year survival proportions.

RESULTS

The search provided 3844 titles and 560 abstracts. Full-text analysis was performed for 176 articles resulting in 21 studies that met the inclusion criteria. Meta-analysis of these studies indicated an estimated survival of implants in implant-supported FPDs of 95.4% (95 percent confidence interval (95% CI): 93.9-96.5%) after 5 and 92.8% (95% CI: 90-94.8%) after 10 years. The survival rate of FPDs supported by implants was 95% (95% CI: 92.2-96.8%) after 5 and 86.7% (95% CI: 82.8-89.8%) after 10 years of function. Only 61.3% (95% CI: 55.3-66.8%) of the patients were free of any complications after 5 years. Peri-implantitis and soft tissue complications occurred in 8.6% (95% CI: 5.1-14.1%) of FPDs after 5 years. Technical complications included implant fractures, connection-related and suprastructure-related complications. The cumulative incidence of implant fractures after 5 years was 0.4% (95% CI: 0.1-1.2%). After 5 years, the cumulative incidence of connection-related complications (screw loosening or fracture) was 7.3% and 14% for suprastructure-related complications (veneer and framework fracture).

CONCLUSION

Despite a high survival of FPDs, biological and technical complications are frequent. This, in turn, means that substantial amounts of chair time have to be accepted by the clinician following the incorporation of implant-supported FPDs. More studies with follow-up times of 10 and more years are needed as only few studies have described the long-term outcomes.

摘要

目的

本系统评价的目的是评估种植体支持的固定局部义齿(FPD)的5年和10年生存率,并描述生物学和技术并发症的发生率。

方法

进行电子MEDLINE检索并辅以手工检索,以识别关于FPD的前瞻性和回顾性队列研究,平均随访时间至少为5年。患者在随访时必须接受临床检查。两名 reviewers 独立进行对已识别研究的评估和数据提取。使用随机效应泊松回归模型分析失败率和并发症发生率,以获得5年和10年生存比例的汇总估计值。

结果

检索提供了3844个标题和560篇摘要。对176篇文章进行了全文分析,最终有21项研究符合纳入标准。对这些研究的荟萃分析表明,种植体支持的FPD中种植体在5年后的估计生存率为95.4%(95%置信区间(95%CI):93.9 - 96.5%),10年后为92.8%(95%CI:90 - 94.8%)。种植体支持的FPD在功能5年后的生存率为95%(95%CI:92.2 - 96.8%),10年后为86.7%(95%CI:82.8 - 89.8%)。5年后只有61.3%(95%CI:55.3 - 66.8%)的患者没有任何并发症。5年后,8.6%(95%CI:5.1 - 14.1%)的FPD发生种植体周围炎和软组织并发症。技术并发症包括种植体骨折、连接相关和上部结构相关并发症。5年后种植体骨折的累积发生率为0.4%(95%CI:0.1 - 1.2%)。5年后,连接相关并发症(螺钉松动或骨折)的累积发生率为7.3%,上部结构相关并发症(贴面和框架骨折)为14%。

结论

尽管FPD的生存率较高,但生物学和技术并发症很常见。这反过来意味着,在采用种植体支持的FPD后,临床医生必须接受大量的椅旁时间。由于只有少数研究描述了长期结果,因此需要更多随访时间为10年及以上的研究。

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