Goldman Dana P, Bao Yuhua
RAND, Santa Monica, CA 90407, USA.
Health Serv Res. 2004 Dec;39(6 Pt 1):1691-712. doi: 10.1111/j.1475-6773.2004.00313.x.
To examine whether highly active antiretroviral therapy (HAART) helps HIV-infected patients return to work, remain employed, and maintain hours of work.
Longitudinal data from a national probability sample of HIV+ patients older than 18 years old who made at least one visit in the contiguous United States in early 1996.
We consider the effect of HAART on three employment outcomes: (1) returning to work within six months of treatment, conditional on not working pretreatment; (2) remaining employed within six months of treatment, conditional on working pretreatment; (3) hours of work conditional on working at the second follow-up survey. We use a bivariate probit model to jointly model employment and treatment with HAART for the first two outcomes and the two-stage least squares method for hours of work. State policies regarding prescription drug coverage are used as instrumental variables for HAART to account for a key source of potential bias-the more severely ill tend to have the most difficulty working, but are also the most likely to be on HAART.
Our results indicate that HAART increases the probability of remaining employed by HIV patients and hours of work for those working within six months of treatment. In the case of remaining employed, the employment effect (an increase from 58 percent to 94 percent in the probability of remaining employed) is statistically significant and the related incremental income is sizable compared to the incremental costs of HAART. Sensitivity analyses demonstrate that the results are robust to different specifications for insurance coverage.
Patients who are working are more likely to remain employed because of treatment with HAART. HAART prescribed to patients in less advanced stages of the infection may lead to the greatest gain in employment.
研究高效抗逆转录病毒疗法(HAART)是否有助于感染人类免疫缺陷病毒(HIV)的患者恢复工作、继续就业并维持工作时长。
来自一个全国概率样本的纵向数据,该样本为1996年初在美国本土至少就诊过一次的18岁以上HIV阳性患者。
我们考察HAART对三种就业结果的影响:(1)在治疗后六个月内恢复工作(前提是治疗前未工作);(2)在治疗后六个月内继续就业(前提是治疗前有工作);(3)在第二次随访调查时有工作的情况下的工作时长。对于前两个结果,我们使用双变量概率模型对就业和HAART治疗进行联合建模,对于工作时长则使用两阶段最小二乘法。将关于处方药覆盖范围的州政策用作HAART的工具变量,以解决潜在偏差的一个关键来源——病情越严重的人往往工作困难越大,但也越有可能接受HAART治疗。
我们的结果表明,HAART提高了HIV患者继续就业的概率以及治疗后六个月内仍在工作的患者的工作时长。就继续就业而言,就业效果(继续就业概率从58%提高到94%)具有统计学意义,与HAART的增量成本相比,相关的增量收入相当可观。敏感性分析表明,结果对保险覆盖范围的不同设定具有稳健性。
正在工作的患者因接受HAART治疗而更有可能继续就业。对感染处于较早期阶段的患者开具HAART可能会带来最大的就业收益。