Ting Shirley Hui Ling, Tan Hwee Cheng, Wong Wai Kwan, Ng Mah Lee, Chan Soh Ha, Ooi Eng Eong
Department of Microbiology, National University of Singapore, Singapore.
Acta Trop. 2004 Nov-Dec;92(3):187-91. doi: 10.1016/j.actatropica.2004.04.010.
Japanese encephalitis virus (JEV) transmission in Singapore appeared to have ceased after pig farming in Singapore was phased out from the early 1980s. However, the recent detection of neutralizing antibodies to JEV in a population of wild boars in an offshore island, as well as the notification of two human cases of JE in Singapore in 2001, prompted us to reconsider the presence and hence the public health threat of JEV in Singapore. We report here a serological study of animals, birds and humans for neutralizing antibodies to JEV. The results indicate that JEV may still be actively transmitted in the peripheral part of the Singapore island and that regular serological surveys of farm animals and birds, such as chickens, may be useful to further elucidate the activity of JEV in Singapore.
自20世纪80年代初新加坡逐步淘汰养猪业后，日本脑炎病毒（JEV）在新加坡的传播似乎已经停止。然而，最近在一个近海岛屿的野猪种群中检测到针对JEV的中和抗体，以及2001年新加坡通报的两例人类日本脑炎病例，促使我们重新考虑JEV在新加坡的存在情况以及由此带来的公共卫生威胁。我们在此报告一项针对动物、鸟类和人类的JEV中和抗体血清学研究。结果表明，JEV可能仍在新加坡岛周边地区活跃传播，对农场动物和鸟类（如鸡）进行定期血清学调查，可能有助于进一步阐明JEV在新加坡的活动情况。
