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完全在体内进行的腹腔镜根治性膀胱切除术并采用可控性尿流改道术(直肠乙状结肠膀胱袋):中期功能和肿瘤学分析

Laparoscopic radical cystectomy with continent urinary diversion (rectosigmoid pouch) performed completely intracorporeally: an intermediate functional and oncologic analysis.

作者信息

DeGer Serdar, Peters Robert, Roigas Jan, Wille Andreas H, Tuerk Ingolf A, Loening Stefan A

机构信息

Department of Urology, Charite-Campus Mitte, Charité University Medicine, Berlin, Germany.

出版信息

Urology. 2004 Nov;64(5):935-9. doi: 10.1016/j.urology.2004.07.004.

Abstract

OBJECTIVES

To present our experience with the first series of rectosigmoid pouch creation performed completely laparoscopically for continent urinary diversion after radical cystectomy to treat transitional cell carcinoma of the bladder. We evaluated the intermediate functional and oncologic outcomes.

METHODS

Between April 2000 and January 2004, 20 patients underwent laparoscopic radical cystectomy with urinary diversion for transitional cell carcinoma at the Department of Urology, Charite Hospital, Campus Mitte. Of the 20 patients, 12 received a rectosigmoid pouch for urinary diversion. The procedures were performed completely laparoscopically, including free-hand laparoscopic suturing and in situ knot tying techniques. The mobilized specimens were removed in an endoscopy bag by way of the rectum or vagina.

RESULTS

All operations were completed laparoscopically by two surgeons without conversion to open surgery. The median operating time was 485 minutes. One patient needed a blood transfusion of 2 U. All specimens had negative surgical margins. Two patients required reoperation. The median follow-up was 33 months. All patients were continent during the day, and 11 patients were continent at night. One patient developed unilateral hydronephrosis with loss of kidney function. No patient developed local recurrence, but 3 patients had systemic progression. Two of the three died of metastatic disease.

CONCLUSIONS

This is the first series of laparoscopic radical cystectomy using an intracorporeal rectosigmoid pouch. Our functional data for continence and upper urinary tract obstruction were comparable with those of open rectosigmoid pouch studies. We were able to demonstrate an oncologic outcome similar to that achieved by the open surgical approach.

摘要

目的

介绍我们在根治性膀胱切除术后完全腹腔镜下创建乙状结肠直肠袋用于可控性尿流改道以治疗膀胱移行细胞癌的首批病例经验。我们评估了中期功能和肿瘤学结果。

方法

2000年4月至2004年1月期间,20例患者在柏林夏里特医学院 Mitte校区泌尿外科接受了腹腔镜根治性膀胱切除术及尿流改道治疗移行细胞癌。20例患者中,12例接受了乙状结肠直肠袋尿流改道。手术完全在腹腔镜下进行,包括徒手腹腔镜缝合和原位打结技术。切除的标本通过直肠或阴道装入内镜袋取出。

结果

所有手术均由两名外科医生在腹腔镜下完成,未转为开放手术。中位手术时间为485分钟。1例患者需要输注2单位血液。所有标本手术切缘均为阴性。2例患者需要再次手术。中位随访时间为33个月。所有患者白天均可自控排尿,11例患者夜间也可自控排尿。1例患者出现单侧肾积水并伴有肾功能丧失。无患者出现局部复发,但3例患者出现全身进展。3例患者中有2例死于转移性疾病。

结论

这是首批使用体内乙状结肠直肠袋的腹腔镜根治性膀胱切除术病例。我们在控尿和上尿路梗阻方面的功能数据与开放乙状结肠直肠袋研究的数据相当。我们能够证明肿瘤学结果与开放手术方法相似。

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