Pisinger Charlotta, Vestbo Jørgen, Borch-Johnsen Knut, Jørgensen Torben
Research Centre for Prevention and Health, Nordre Ringvej, DK-2600 Glostrup University Hospital, Glostrup, Denmark.
Prev Med. 2005 Mar;40(3):285-92. doi: 10.1016/j.ypmed.2004.06.001.
Several large and well-conducted community interventions have failed to detect an effect on prevalence of smoking.
Two thousand four hundred eight daily smokers in all motivational stages were actively recruited and included in a randomised population-based intervention study in Copenhagen, Denmark. All smokers completed a questionnaire and underwent a health examination and a lifestyle consultation. Daily smokers in the high intensity intervention group were offered assistance to quit in smoking cessation groups.
The validated abstinence rate at 1-year follow-up was 16.3% in the high intensity group and 12.7% in the low intensity group compared with a self-reported abstinence rate of 7.3% in the background population. The adjusted odds ratio of abstinence in the high intervention group was significantly higher, OR = 2.2 (1.6-3.0) than in the background population, also in the 'intention-to-treat' analyses, OR = 1.5 (1.1-2.0). Higher socioeconomic status, higher age at onset of daily smoking, and a higher wish to quit were predictors of success.
In a population-based setting, using active recruitment and offering assistance to quit, it was possible to include many smokers and to achieve a significantly higher validated abstinence in the high intensity intervention than in the background population, even when using 'intention-to-treat' analyses.
多项大型且实施良好的社区干预未能发现对吸烟流行率有影响。
积极招募了处于所有动机阶段的2408名每日吸烟者，并将其纳入丹麦哥本哈根一项基于人群的随机干预研究。所有吸烟者均完成一份问卷，并接受健康检查和生活方式咨询。高强度干预组的每日吸烟者在戒烟小组中获得戒烟帮助。
高强度组1年随访时经验证的戒烟率为16.3%，低强度组为12.7%，而背景人群自我报告的戒烟率为7.3%。在“意向性分析”中，高强度干预组戒烟的调整优势比显著高于背景人群，比值比（OR）=2.2（1.6 - 3.0），在“意向性分析”中OR = 1.5（1.1 - 2.0）。较高的社会经济地位、开始每日吸烟时较高的年龄以及较高的戒烟意愿是成功的预测因素。
在基于人群的环境中，通过积极招募并提供戒烟帮助，即使采用“意向性分析”，也有可能纳入许多吸烟者，并使高强度干预组经验证的戒烟率显著高于背景人群。
