疟疾和心力衰竭中的恶病质：临床实践中的治疗考量
Cachexia in malaria and heart failure: therapeutic considerations in clinical practice.
作者信息
Onwuamaegbu M E, Henein M, Coats A J
机构信息
Department of Clinical Cardiology, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK.
出版信息
Postgrad Med J. 2004 Nov;80(949):642-9. doi: 10.1136/pgmj.2004.020891.
Abstract
Cachexia is an independent prognostic marker of survival in many chronic diseases including heart failure and malaria. Morbidity and mortality from malaria is high in most of the third world where it presents a very challenging public health problem. Malaria may present in the UK as fever in the returning traveller or as fever in overseas visitors. How and why cachexia develops in malaria in a manner similar to the cachexia of chronic heart failure and the treatment strategies that would alter outcomes in both diseases are discussed in this review.
摘要
恶病质是包括心力衰竭和疟疾在内的许多慢性疾病中生存的独立预后标志物。在大多数第三世界国家，疟疾的发病率和死亡率很高，这是一个极具挑战性的公共卫生问题。在英国，疟疾可能表现为归国旅行者的发热或海外访客的发热。本文综述了疟疾中恶病质如何以及为何以类似于慢性心力衰竭恶病质的方式发展，以及能够改变这两种疾病预后的治疗策略。
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