Glazowski M J, Ostergaard G Z, Arpi M, Thomsen M
Børneafdelingen, klinisk mikrobiologisk afdeling, Hvidovre Hospital, København.
Ugeskr Laeger. 1992 Mar 23;154(13):868-9.
A case of the toxic shock syndrome (TSS) in a burnt (scalded) child is presented. TSS is a condition most frequently associated with menstruating women using tampons. In recent years, however, increased knowledge of the syndrome has led to an increase in the number of reported cases associated with other clinical situations. The non-menstrual cases are most frequently observed in young persons many of whom are children. TSS is due to infection with toxin-producing S. aureus. TSS-toxin-1 is apparently the most important among toxins. The fatality rate has been reported to be as high as 15%, so recognition of the syndrome and institution of the correct treatment are of utmost importance. By means of an easy and rapid test, it is possible to detect if the strain of S. aureus is TSST-1-producing. The test is now available and employs passive latex agglutination. The sensitivity and specificity are high and, if clinical signs of TSS are present, a positive test result will support the diagnosis in 94% of alle positive cases.
本文报告了一例烧伤（烫伤）儿童的中毒性休克综合征（TSS）。TSS是一种最常与使用卫生棉条的月经期女性相关的病症。然而，近年来，对该综合征认识的增加导致了与其他临床情况相关的报告病例数有所增加。非月经期病例最常见于年轻人，其中许多是儿童。TSS是由产生毒素的金黄色葡萄球菌感染所致。TSS毒素-1显然是毒素中最重要的一种。据报道，病死率高达15%，因此识别该综合征并采取正确的治疗措施至关重要。通过一种简便快速的检测方法，可以检测金黄色葡萄球菌菌株是否产生TSST-1。该检测方法现已可用，采用被动乳胶凝集法。其敏感性和特异性都很高，如果存在TSS的临床症状，在所有阳性病例中，检测结果呈阳性将在94%的病例中支持诊断。
