Ehling-Schulz Monika, Fricker Martina, Scherer Siegfried
Abt. Mikrobiologie, ZIEL, Technische Universität München, Freising, Germany.
Mol Nutr Food Res. 2004 Dec;48(7):479-87. doi: 10.1002/mnfr.200400055.
Bacillus cereus is the causative agent of two distinct forms of gastroenteritic disease connected to food-poisoning. It produces one emesis-causing toxin and three enterotoxins that elicit diarrhea. Due to changing lifestyles and eating habits, B. cereus is responsible for an increasing number of food-borne diseases in the industrial world. In the past, most studies concentrated on the diarrhoeal type of food-borne disease, while less attention has been given to the emetic type of the disease. The toxins involved in the diarrhoeal syndrome are well-known and detection methods are commercially available, whereas diagnostic methods for the emetic type of disease have been limited. Only recently, progress has been made in developing identification methods for emetic B. cereus and its corresponding toxin. We will summarize the data available for the emetic type of the disease and discuss some new insights in emetic strain characteristics, diagnosis, and toxin synthesis.
蜡样芽孢杆菌是与食物中毒相关的两种不同形式的胃肠疾病的病原体。它产生一种致呕吐毒素和三种引发腹泻的肠毒素。由于生活方式和饮食习惯的改变，蜡样芽孢杆菌在工业化国家导致的食源性疾病数量不断增加。过去，大多数研究集中在腹泻型食源性疾病上，而对呕吐型疾病的关注较少。腹泻综合征所涉及的毒素是众所周知的，检测方法也有商业供应，而呕吐型疾病的诊断方法却很有限。直到最近，在开发呕吐型蜡样芽孢杆菌及其相应毒素的鉴定方法方面才取得了进展。我们将总结有关呕吐型疾病的现有数据，并讨论呕吐型菌株特征、诊断和毒素合成方面的一些新见解。
