Bhutta Zulfiqar A, Khan Iqtidar, Salat Suhail, Raza Farukh, Ara Husan
Aga Khan University, Karachi 74800, Pakistan.
BMJ. 2004 Nov 13;329(7475):1151-5. doi: 10.1136/bmj.329.7475.1151.
Clinical care of infants with a very low birth weight (less than 1500 g) in developing countries can be labour intensive and is often associated with a prolonged stay in hospital. The Aga Khan University Medical Center in Karachi, Pakistan, established a neonatal intensive care unit in 1987. By 1993-4, very low birthweight infants remained in hospital for 18-21 days.
A stepdown unit was established in September 1994, with mothers providing all basic nursing care for their infants before being discharged under supervision.
We analysed neonatal outcomes for the time periods before and after the stepdown unit was created (1987-94 and 1995-2001). We compared these two time periods for survival after birth until discharge, morbidity patterns during hospitalisation, length of stay in hospital, and readmission rates to hospital in the four weeks after discharge.
Of 509 consecutive, very low birthweight infants, 494 (97%) preterm and 140 (28%) weighing < 1000 g at birth), 391 (76%) survived to discharge from the hospital. The length of hospitalisation fell significantly from 1987-90, when it was 34 (SD 18) days, to 16 (SD 14) days in 1999-2001 (P < 0.001). Readmission rates to hospital did not rise, nor did adverse outcomes at 12 months of age.
Our results indicate that it is possible to involve mothers in the active care of their very low birthweight infants before discharge. This may translate into earlier discharge from hospital to home settings without any increase in short term complications and readmissions.
在发展中国家,对极低出生体重(低于1500克)婴儿的临床护理可能需要耗费大量人力,而且这些婴儿往往需要长时间住院。巴基斯坦卡拉奇的阿迦汗大学医学中心于1987年设立了新生儿重症监护病房。到1993 - 1994年,极低出生体重婴儿的住院时间为18 - 21天。
1994年9月设立了一个降级护理病房,母亲们在接受监督下出院前为婴儿提供所有基本护理。
我们分析了降级护理病房设立前后(1987 - 1994年和1995 - 2001年)的新生儿结局。我们比较了这两个时间段从出生到出院的存活率、住院期间的发病模式、住院时间以及出院后四周内的再入院率。
在509例连续的极低出生体重婴儿中(494例[97%]为早产儿,140例[28%]出生时体重<1000克),391例(76%)存活至出院。住院时间从1987 - 1990年的34(标准差18)天显著降至1999 - 2001年的16(标准差14)天(P<0.001)。再入院率没有上升,12个月龄时的不良结局也没有增加。
我们的结果表明,让母亲在极低出生体重婴儿出院前积极参与护理是可行的。这可能会使婴儿更早出院回家,且不会增加短期并发症和再入院率。