Albrektsson Tomas, Wennerberg Ann
Department of Biomaterials/Handicap Research, Institute for Surgical Sciences, Göteborg University, Sweden.
Int J Prosthodont. 2004 Sep-Oct;17(5):536-43.
This article reviews the topographic and chemical properties of different oral implant surfaces and in vivo responses to them.
The article considers detailed mechanical, topographic, and physical characteristics of implant surfaces. Anchorage mechanisms such as biomechanical and biochemical bonding are examined. Osteoattraction and doped surfaces are discussed.
Surface quality of an oral implant may be subdivided into mechanical, topographic, and physicochemical properties. Topographic properties are evaluated at the micrometer level of resolution. Moderately rough surfaces (Sa between 1.0 and 2.0 microm) show stronger bone responses than smoother or rougher surfaces. The majority of currently marketed implants are moderately rough. Oral implants permit bone ingrowth into minor surface irregularities-biomechanical bonding or osseointegration. Additional biochemical bonding seems possible with certain surfaces. Osteoattraction is a commercial term without precise biologic correspondence. Surfaces doped with biochemical agents such as bone growth factors have been developed.
Moderately roughened surfaces seem to have some clinical advantages over smoother or rougher surfaces, but the differences are small and often not statistically significant. Bioactive implants may offer some promise.
本文综述了不同口腔种植体表面的形貌和化学性质以及机体对它们的体内反应。
本文考虑了种植体表面详细的机械、形貌和物理特性。研究了诸如生物力学和生化结合等锚固机制。讨论了骨吸引和掺杂表面。
口腔种植体的表面质量可细分为机械、形貌和物理化学性质。形貌性质在微米级分辨率下进行评估。中等粗糙度的表面(Sa在1.0至2.0微米之间)比更光滑或更粗糙的表面显示出更强的骨反应。目前市场上销售的大多数种植体是中等粗糙度的。口腔种植体允许骨长入微小的表面不规则处——生物力学结合或骨整合。某些表面似乎还可能存在额外的生化结合。骨吸引是一个没有精确生物学对应关系的商业术语。已开发出掺杂有诸如骨生长因子等生化剂的表面。
中等粗糙度的表面似乎比更光滑或更粗糙的表面具有一些临床优势,但差异很小且通常无统计学意义。生物活性种植体可能具有一定前景。