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免疫功能正常患者的原发性淋巴皮肤诺卡菌病。

Primary lymphocutaneous nocardiosis in an immunocompetent patient.

作者信息

Maraki Sofia, Chochlidakis Stavros, Nioti Eleni, Tselentis Yannis

机构信息

Department of Clinical Bacteriology, Parasitology, Zoonoses and Geographical Medicine, University Hospital of Crete, 712 01 Heraklion, Crete, Greece.

出版信息

Ann Clin Microbiol Antimicrob. 2004 Nov 15;3:24. doi: 10.1186/1476-0711-3-24.

DOI:10.1186/1476-0711-3-24
PMID:15544704
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC534796/
Abstract

BACKGROUND

Nocardia brasiliensis is a rare human pathogen usually associated with localized cutaneous infections.

CASE PRESENTATION

We report a case of primary lymphocutaneous Nocardia brasiliensis infection developed after a bone fracture of the left hand of an otherwise healthy 32-year-old man. Treatment with trimethoprim-sulfamethoxazole given for a total of three months combined with surgical debridement resulted in complete resolution of the infection.

CONCLUSION

Nocardiosis should be part of the differential diagnosis in patients with sporotrichoid infection, particularly those with a history of outdoor injury. Culture of the affected tissue and antimicrobial susceptibility testing of the isolate should be performed for diagnosis and treatment.

摘要

背景

巴西奴卡菌是一种罕见的人类病原体,通常与局部皮肤感染有关。

病例报告

我们报告一例原发性淋巴皮肤型巴西奴卡菌感染病例,该病例发生在一名32岁身体健康的男性左手骨折后。给予复方磺胺甲恶唑治疗共三个月,并结合手术清创,感染得以完全消退。

结论

奴卡菌病应作为孢子丝菌病样感染患者鉴别诊断的一部分,尤其是有户外受伤史的患者。应对受影响组织进行培养,并对分离株进行药敏试验,以用于诊断和治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30af/534796/cf0bea1e3967/1476-0711-3-24-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30af/534796/cf0bea1e3967/1476-0711-3-24-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30af/534796/cf0bea1e3967/1476-0711-3-24-1.jpg

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Diagn Microbiol Infect Dis. 2003 Sep;47(1):341-4. doi: 10.1016/s0732-8893(03)00090-7.
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Report of human nocardiosis in Italy between 1993 and 1997.1993年至1997年意大利人体诺卡菌病报告。
Eur J Epidemiol. 2001;17(11):1019-22. doi: 10.1023/a:1020010826300.
3
Identification of medically relevant Nocardia species with an abbreviated battery of tests.使用简化检测组合鉴定医学相关诺卡菌属菌种。
昆虫叮咬后罕见的淋巴细胞性皮肤蜂窝织炎:原发性皮肤诺卡菌病1例报告及文献复习
Infez Med. 2022 Jun 1;30(2):285-292. doi: 10.53854/liim-3002-15. eCollection 2022.
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Primary Lymphocutaneous in an Immunocompetent Host: Case Report and Literature Review.原发性皮肤黏膜淋球菌感染 1 例报告并文献复习。
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5
Isolated Nocardiosis, an Unrecognized Primary Immunodeficiency?孤立性奴卡菌病,一种未被认识的原发性免疫缺陷病?
Front Immunol. 2020 Oct 20;11:590239. doi: 10.3389/fimmu.2020.590239. eCollection 2020.
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First Case of Causing Primary Cutaneous Nocardiosis in an Immunocompetent Patient.首例免疫功能正常患者原发性皮肤诺卡菌病。
J Investig Med High Impact Case Rep. 2020 Jan-Dec;8:2324709620938228. doi: 10.1177/2324709620938228.
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