Kim Karen H, Geronemus Roy G
Laser and Skin Surgery Center of New York, 317 E. 34th Street, New York, NY 10016, USA.
Arch Facial Plast Surg. 2004 Nov-Dec;6(6):398-409. doi: 10.1001/archfaci.6.6.398.
Multiple modalities have been described for skin rejuvenation, including ablative and nonablative therapies. Because of the prolonged recovery period associated with ablative procedures that injure the epidermis, nonablative skin treatments have grown increasingly popular. Various laser- and light-based systems have been designed or applied for promoting skin remodeling without damage to the epidermis.
Studies investigating the use of nonablative procedures for facial rhytids or acne scarring with clinical, histological, and objective quantitative measurements are systematically reviewed.
Nonablative treatments are associated with clinical and objective improvements for the treatment of facial rhytids and acne scarring. Dermal remodeling seems to occur as a result of thermal injury, leading to dermal fibrosis without epidermal disruption.
Although results are not as impressive as those of ablative treatments, nonablative procedures are effective in the treatment of photoaging and acne scarring. As technology in nonablative therapies continues to evolve, future laser and light sources may yield even more favorable results.
已描述了多种用于皮肤年轻化的方法，包括剥脱性和非剥脱性疗法。由于剥脱性手术会损伤表皮，恢复期较长，非剥脱性皮肤治疗越来越受欢迎。已设计或应用了各种基于激光和光的系统来促进皮肤重塑而不损伤表皮。
系统回顾了通过临床、组织学和客观定量测量来研究非剥脱性方法用于治疗面部皱纹或痤疮瘢痕的研究。
非剥脱性治疗在治疗面部皱纹和痤疮瘢痕方面与临床和客观改善相关。热损伤似乎导致真皮重塑，从而导致真皮纤维化而无表皮破坏。
尽管结果不如剥脱性治疗令人印象深刻，但非剥脱性方法在治疗光老化和痤疮瘢痕方面有效。随着非剥脱性疗法技术的不断发展，未来的激光和光源可能会产生更理想的效果。
