[急性中毒性脑病的影像学检查]

[Imaging in acute toxic encephalopathy].

作者信息

Dietemann J-L, Botelho C, Nogueira T, Vargas M I, Audibert C, Abu Eid M, Bogorin A, Bernardo R, Jacques C, Kremer S, Zöllner G

机构信息

Service de Radiologie 2, Hôpitaux Universitaires--Hôpital de Hautepierre, Avenue Molière, 67098 Strasbourg Cedex, France.

出版信息

J Neuroradiol. 2004 Sep;31(4):313-26. doi: 10.1016/s0150-9861(04)97010-1.

DOI:10.1016/s0150-9861(04)97010-1

PMID:15545943

Abstract

Neuroimaging, particularly MR imaging, plays a major role for the diagnosis of many acute toxic encephalopathies. Toxic disorders are related to drugs (immunosuppressive agents, chemotherapeutic agents, anti-epileptic drugs, heroin...), to metals (lead, manganese, mercury...), and to industrial and environmental chemicals (solvent, carbon monoxide...). MR imaging with diffusion and perfusion imaging provides information regarding brain lesions induced by the toxic agents (vasogenic edema, cytotoxic edema, infarction, hemorrhage, demyelination...).

摘要

神经影像学，尤其是磁共振成像（MR成像），在许多急性中毒性脑病的诊断中起着重要作用。中毒性疾病与药物（免疫抑制剂、化疗药物、抗癫痫药物、海洛因等）、金属（铅、锰、汞等）以及工业和环境化学物质（溶剂、一氧化碳等）有关。结合扩散加权成像和灌注成像的MR成像可提供有关毒物所致脑损伤（血管源性水肿、细胞毒性水肿、梗死、出血、脱髓鞘等）的信息。