纳米多孔碳化硅：一种用于生物医学应用的候选半透性材料。
Nanoporous SiC: a candidate semi-permeable material for biomedical applications.
作者信息
Rosenbloom A J, Sipe D M, Shishkin Y, Ke Y, Devaty R P, Choyke W J
机构信息
Molecular Biosensors and Imaging Center, Carnegie Mellon University, Pittsburgh, PA 15213, USA.
出版信息
Biomed Microdevices. 2004 Dec;6(4):261-7. doi: 10.1023/B:BMMD.0000048558.91401.1d.
We have fabricated free-standing SiC nanoporous membranes in both p -type and n -type material. We showed that these membranes will permit the diffusion of proteins up to 29000 Daltons, while excluding larger proteins. By using radioactively labeled albumin, we also show that porous SiC has very low protein adsorption, comparable to the best commercially available polymer nanoporous membrane.
我们已经制备出了p型和n型的独立式碳化硅纳米多孔膜。我们发现这些膜能够允许分子量高达29000道尔顿的蛋白质扩散，同时排斥更大的蛋白质。通过使用放射性标记的白蛋白，我们还表明多孔碳化硅的蛋白质吸附率非常低，与市售最好的聚合物纳米多孔膜相当。
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