Söderberg Stig, Kullgren Gunnar, Salander Renberg Ellinor
Dept. of Clinical Sciences, Psychiatry Umeå University, 901 85 Umeå, Sweden.
Soc Psychiatry Psychiatr Epidemiol. 2004 Nov;39(11):916-20. doi: 10.1007/s00127-004-0839-0.
There is substantial empirical research linking borderline personality disorder with prolonged mental instability and recurrent suicidality. At the same time, a growing body of observations links borderline personality disorder to sexual abuse and other forms of abuse and trauma in childhood. The aim of this study was to investigate among patients admitted for parasuicide the predictive value for outcome 7 years after the parasuicide of a diagnosis of borderline personality disorder compared to the predictive value of a history of childhood sexual abuse.
Semi-structured interviews were conducted at the time of the index parasuicide, with follow-up interviews 7 years later. In addition, information was collected from medical records at the psychiatric clinic. A logistic regression analysis was used to assess the specific influence of the covariates borderline personality disorder, gender and reported childhood sexual abuse on the outcome variables.
Univariate regression analysis showed higher odds ratios for borderline personality disorder, female gender and childhood sexual abuse regarding prolonged psychiatric contact and repeated parasuicides. A combined logistic regression model found significantly higher odds ratios only for childhood sexual abuse with regard to suicidal ideation, repeated parasuicidal acts and more extensive psychiatric support.
The findings support the growing body of evidence linking the characteristic symptoms of borderline personality disorder to childhood sexual abuse, and identify sexual abuse rather than a diagnosis of borderline personality disorder as a predictor for poor outcome after a parasuicide. The findings are relevant to our understanding and treatment of parasuicide patients, especially those who fulfil the present criteria for borderline personality disorder.
有大量实证研究将边缘型人格障碍与长期精神不稳定和反复自杀行为联系起来。与此同时,越来越多的观察结果将边缘型人格障碍与童年期的性虐待以及其他形式的虐待和创伤联系在一起。本研究的目的是在自杀未遂入院患者中,比较边缘型人格障碍诊断对自杀未遂7年后结局的预测价值与童年期性虐待史的预测价值。
在首次自杀未遂时进行半结构化访谈,并在7年后进行随访访谈。此外,还从精神科诊所的病历中收集信息。采用逻辑回归分析来评估协变量边缘型人格障碍、性别和报告的童年期性虐待对结局变量的具体影响。
单因素回归分析显示,边缘型人格障碍、女性性别和童年期性虐待在长期精神科接触和反复自杀未遂方面的比值比更高。一个综合逻辑回归模型发现,仅童年期性虐待在自杀意念、反复自杀未遂行为和更广泛的精神科支持方面的比值比显著更高。
这些发现支持了越来越多的证据,即将边缘型人格障碍的特征性症状与童年期性虐待联系起来,并确定性虐待而非边缘型人格障碍的诊断是自杀未遂后不良结局的预测因素。这些发现与我们对自杀未遂患者的理解和治疗相关,尤其是那些符合目前边缘型人格障碍标准的患者。