Ozcan Cengiz, Talas Derya, Görür Kemal, Aydin Ozlem, Yildiz Altan
Department of Otorhinolaryngology, Mersin University School of Medicine, Mersin, Turkey.
Eur Arch Otorhinolaryngol. 2005 May;262(5):412-5. doi: 10.1007/s00405-004-0832-y. Epub 2004 Nov 12.
Actinomycosis is a rare chronic infectious disease caused by Actinomyces israelii, which is an anaerobic filamentous, gram-positive saprophyte organism of the oral cavity. Historically, these bacteria were known as fungi because of their light microscopic appearance. Actinomycosis consists of three different forms: cervico-facial (the most common form), abdominal and pulmonothoracic. It commonly involves the head and neck region including the mandible, paranasal sinuses, lacrimal gland, parotid gland and orbit. Poor oral hygiene and dental diseases have been known to be the source of actinomycosis. Actinomycosis is diagnosed with positive culture or detecting actinomyces colonies and sulfur granules in histopathologic specimens. The treatment of choice is surgical excision of the lesion and long-term penicillin therapy. Actinomycosis of the internal nose is extremely rare. There was only one nasal septum actinomycosis reported in the English literature, but there was no lateral nasal wall actiomycosis regarding the turbinate. Therefore, actinomycosis should not be overlooked for the differential diagnosis of intra-nasal lesions for the initiation of appropriate and early treatment.
放线菌病是一种由以色列放线菌引起的罕见慢性感染性疾病,以色列放线菌是口腔中的一种厌氧丝状革兰氏阳性腐生菌。从历史上看,由于其在光学显微镜下的外观,这些细菌被认为是真菌。放线菌病有三种不同形式:颈面部(最常见的形式)、腹部和肺胸型。它通常累及头颈部区域,包括下颌骨、鼻窦、泪腺、腮腺和眼眶。已知口腔卫生差和牙齿疾病是放线菌病的来源。放线菌病通过在组织病理学标本中培养阳性或检测到放线菌菌落和硫颗粒来诊断。首选治疗方法是手术切除病变并长期使用青霉素治疗。鼻内放线菌病极为罕见。英文文献中仅报道过一例鼻中隔放线菌病,但关于鼻甲的鼻侧壁放线菌病尚无报道。因此,在对鼻内病变进行鉴别诊断以启动适当的早期治疗时,不应忽视放线菌病。