Levitt M D, Kamm M A, Groom J, Hawley P R, Nicholls R J
Department of Physiology, St. Mark's Hospital, London, UK.
Br J Surg. 1992 Feb;79(2):126-8. doi: 10.1002/bjs.1800790210.
Measurement of intrapouch pressure during continuous distension with water (pouchmetrography) was performed in ten patients with good pouch function after restorative proctocolectomy and a 'normal' baseline pressure curve was constructed from the mean pressures at 50-ml intervals. Eight other patients with poor pouch function were studied and the two groups were compared. Patients with poor function had significantly lower maximum tolerated volumes (297.5 versus 565 ml, P less than 0.02) and volumes which caused urgency (135 versus 265 ml, P less than 0.02). Baseline pressure curves were above the upper limit of the normal range (mean plus two standard deviations) for a substantial proportion of the recording in six of the patients with poor function. Large, isolated contraction waves were recorded in six of ten patients with good function and in three of those with poor function. Rhythmic waves were frequently seen in both groups but were more prominent in patients with poor function. Pouchmetrography is a provocative test of pouch motor function which may unmask abnormal muscle activity resulting from reduced compliance or a primary motility disorder.
对十例在保留直肠结肠切除术术后储袋功能良好的患者进行了水持续扩张期间的储袋内压力测量（储袋测压法），并根据50毫升间隔的平均压力构建了“正常”基线压力曲线。研究了其他八例储袋功能差的患者，并对两组进行了比较。功能差的患者最大耐受容量显著更低（297.5对565毫升，P<0.02）以及引起尿急的容量更低（135对265毫升，P<0.02）。在六例功能差的患者中，相当比例的记录中基线压力曲线高于正常范围上限（均值加两个标准差）。在十例功能良好的患者中有六例以及功能差的患者中有三例记录到了大的孤立收缩波。两组中均频繁见到节律性波，但在功能差的患者中更明显。储袋测压法是一种对储袋运动功能的激发试验，它可能会揭示因顺应性降低或原发性运动障碍导致的异常肌肉活动。
