Schenck John F
General Electric Global Research Center, Building K1/NMR, 1 Research Drive, Schenectady, NY 13209, USA.
Prog Biophys Mol Biol. 2005 Feb-Apr;87(2-3):185-204. doi: 10.1016/j.pbiomolbio.2004.08.009.
Clinical magnetic resonance imaging (MRI) was introduced in the early 1980s and has become a widely accepted and heavily utilized medical technology. This technique requires that the patients being studied be exposed to an intense magnetic field of a strength not previously encountered on a wide scale by humans. Nonetheless, the technique has proved to be very safe and the vast majority of the scans have been performed without any evidence of injury to the patient. In this article the history of proposed interactions of magnetic fields with human tissues is briefly reviewed and the predictions of electromagnetic theory on the nature and strength of these interactions are described. The physical basis of the relative weakness of these interactions is attributed to the very low magnetic susceptibility of human tissues and the lack of any substantial amount of ferromagnetic material normally occurring in these tissues. The presence of ferromagnetic foreign bodies within patients, or in the vicinity of the scanner, represents a very great hazard that must be scrupulously avoided. As technology and experience advance, ever stronger magnetic field strengths are being brought into service to improve the capabilities of this imaging technology and the benefits to patients. It is imperative that vigilance be maintained as these higher field strengths are introduced into clinical practice to assure that the high degree of patient safety that has been associated with MRI is maintained.
临床磁共振成像(MRI)于20世纪80年代初问世,现已成为一种被广泛接受且广泛应用的医学技术。这项技术要求接受检查的患者暴露于一种强度的强磁场中,而这种强度的磁场此前人类并未广泛接触过。尽管如此,该技术已被证明非常安全,绝大多数扫描都是在没有任何对患者造成损伤迹象的情况下进行的。在本文中,我们简要回顾了磁场与人体组织相互作用的研究历史,并描述了电磁理论对这些相互作用的性质和强度的预测。这些相互作用相对较弱的物理基础归因于人体组织的极低磁化率以及这些组织中通常不存在任何大量铁磁性物质。患者体内或扫描仪附近存在铁磁性异物是一种必须严格避免的巨大危险。随着技术和经验的进步,越来越强的磁场强度被投入使用,以提高这种成像技术的能力以及给患者带来的益处。当这些更高的磁场强度引入临床实践时,必须保持警惕,以确保维持与MRI相关的高度患者安全性。