Magnavita N, Fileni A
Istituto di Medicina del Lavoro, Università Cattolica del Sacro Cuore, Roma.
Radiol Med. 1995 May;89(5):662-6.
It was observed that "medical diagnosis utilizing Magnetic Resonance (MR) scanners may be one of the first modalities in which there is more risk for the operator of the equipment than for the patient" (Young, 1984). Despite this statement, only a few studies have been devoted to the assessment of occupational hazard in MR imaging personnel. The principal features associated with MR systems are: static magnetic fields, time-varying magnetic fields, and radiofrequency irradiation. Potential medical effects related to these hazards are reviewed. Static magnetic fields are known to induce in vitro changes in enzyme kinetics, orientation changes of macromolecules and subcellular components, distortion of ion currents and magnetohydrodynamic effects. Possible mechanisms for static magnetic field bioeffects include the exertion of magnetic forces, the induction of voltages, and other mechanisms (proton tunneling, ion cyclotron resonance) that are yet scarcely known. Human epidemiological studies on static magnetic fields are mainly based on subjective observations, and lack adequate control for confounding factors. Time-varying magnetic fields in the extremely-low frequency range have been associated with both occupational and non-occupational adverse health effects. Exposure to electromagnetic fields in office workers has been related to an increased rate of abortion; the vast majority of studies in this field, however, did not reach any significant result. Many literature reports support the evidence of an elevation of cancer risk in subjects exposed to residential and occupational ELF fields. Although such observations are not yet proved, the alleged occupational risk in magnetic fields exposure should induce to optimize exposure in MR imaging workers.
据观察,“利用磁共振(MR)扫描仪进行医学诊断可能是设备操作人员比患者面临更多风险的首批检查方式之一”(扬,1984年)。尽管有此说法,但仅有少数研究致力于评估磁共振成像工作人员的职业危害。与磁共振系统相关的主要特征有:静磁场、随时间变化的磁场以及射频辐射。本文综述了与这些危害相关的潜在医学影响。已知静磁场会在体外引起酶动力学变化、大分子和亚细胞成分的取向变化、离子电流畸变以及磁流体动力学效应。静磁场生物效应的可能机制包括磁力作用、电压感应以及其他尚鲜为人知的机制(质子隧穿、离子回旋共振)。关于静磁场的人体流行病学研究主要基于主观观察,且缺乏对混杂因素的充分控制。极低频范围内随时间变化的磁场已被证实与职业和非职业性不良健康影响有关。办公室工作人员接触电磁场与流产率上升有关;然而,该领域的绝大多数研究并未得出任何显著结果。许多文献报告支持了接触住宅和职业极低频场的人群患癌风险升高的证据。尽管此类观察结果尚未得到证实,但据称磁场暴露的职业风险应促使优化磁共振成像工作人员的暴露情况。