Sparer Judy, Stowe Meredith H, Bello Dhimiter, Liu Youcheng, Gore Rebecca J, Youngs Fred, Cullen Mark R, Redlich Carrie A, Woskie Susan R
Yale Occupational and Environmental Medicine Program, Yale School of Medicine, New Haven, CT 06510, USA.
J Occup Environ Hyg. 2004 Sep;1(9):570-81. doi: 10.1080/15459620490485909.
Isocyanates, known to cause respiratory sensitization and asthma, are widely used in automotive refinishing where exposures to aliphatic polyisocyanates occur by both inhalation and skin contact. The work reported here, the characterization of isocyanate exposure in the autobody industry, was part of an epidemiologic study of workers in 37 autobody shops in Connecticut. This article describes workplaces, tasks, and controls, and outlines the frequency, duration, and intensity of isocyanate exposures. Personal air samples taken outside of respirators had median concentrations of 66.5 microg NCO/m3 for primer, 134.4 microg (NCO)/m3 for sealer, and 358.5 microg NCO/m3 for clearcoat. Forty-eight percent of primer, 66% of sealer, and 92% of clearcoat samples exceeded the United Kingdom Health and Safety Executive guideline for isocyanate, though none exceeded the National Institute for Occupational Safety and Health (NIOSH) recommended exposure limit for monomer. Nonisocyanate-containing primers and sealers are used in more than half the shops, but nonisocyanate clearcoats are rare. Eighty-two percent of personal samples taken within a spray booth exceeded the U.K. guideline: 81% of those in downdraft spray booths, 74% in semidowndraft booths, and 92% in crossdraft booths. Only 8% of shops reported that spraying is done exclusively in spray booths. All painters wore some type of respirator. In 30% of shops, painters used supplied air respirators; the rest relied on half face organic vapor cartridge respirators with N95 overspray pads. All shops provided some type of gloves, usually latex, not recommended for isocyanate protection. Despite improvements in autobody shop materials, practices, and controls, there are still opportunities for substantial exposures to isocyanates.
异氰酸酯已知会导致呼吸道过敏和哮喘,广泛应用于汽车修补漆行业,在该行业中,人们会通过吸入和皮肤接触而暴露于脂肪族多异氰酸酯中。本文所报告的工作,即汽车车身行业异氰酸酯暴露情况的特征描述,是对康涅狄格州37家汽车车身修理店工人进行的一项流行病学研究的一部分。本文描述了工作场所、任务和控制措施,并概述了异氰酸酯暴露的频率、持续时间和强度。在呼吸防护器外部采集的个人空气样本中,底漆的异氰酸酯中位浓度为66.5微克NCO/立方米,密封剂为134.4微克(NCO)/立方米,清漆为358.5微克NCO/立方米。48%的底漆样本、66%的密封剂样本和92%的清漆样本超过了英国健康与安全执行局的异氰酸酯指导限值,不过没有一个样本超过美国国家职业安全与健康研究所(NIOSH)推荐的单体暴露限值。超过半数的修理店使用不含异氰酸酯的底漆和密封剂,但不含异氰酸酯的清漆很少见。在喷漆房内采集的个人样本中有82%超过了英国的指导限值:下行通风喷漆房内的样本中有81%,半下行通风喷漆房内的样本中有74%,横向通风喷漆房内的样本中有92%。只有8%的修理店报告称喷漆完全在喷漆房内进行。所有喷漆工都佩戴了某种类型的呼吸防护器。在30%的修理店中,喷漆工使用供气式呼吸防护器;其余的则依靠配有N95防喷溅垫的半面罩有机蒸气滤毒罐呼吸防护器。所有修理店都提供了某种类型的手套,通常是乳胶手套,不推荐用于防护异氰酸酯。尽管汽车车身修理店在材料、操作和控制方面有所改进,但仍然存在大量接触异氰酸酯的机会。