Ando Yoshiya, Ekuni Yutaka, Matsumoto Yoshinari, Nakano Shiro, Saito Kensuke, Kakimoto Kazuhiro, Tanigawa Takuo, Kawa Motohiro, Toyama Takenori
Wakayama Medical University, Kihoku Hospital, Obstetrics and Gynecology, Wakayama, Japan.
J Obstet Gynaecol Res. 2004 Dec;30(6):436-8. doi: 10.1111/j.1447-0756.2004.00227.x.
Human T-lymphotropic virus type-I (HTLV-I) infection occurs via mothers' milk during feeding. However, freeze-thaw processing can eliminate the infectivity of the mother's milk of HTLV-I carriers.
A long-term follow-up survey was conducted to investigate the HTLV-I infectivity of frozen-thawed mothers' milk among infants whose mothers were HTLV-I seropositive.
Infants fed frozen-thawed mothers' milk did not become HTLV-I antibody-positive up until 1 year old, and all children followed up until an age of 11-12 years were antibody negative.
This study showed that freeze-thaw processing can eliminate the HTLV-I infectivity of mothers' milk, and that HTLV-I carriers can indirectly feed their infants using frozen-thawed mothers' milk as a way to prevent HTLV-I infection.
人类嗜T淋巴细胞病毒I型（HTLV-I）感染可在哺乳期间通过母乳发生。然而，冻融处理可消除HTLV-I携带者母乳的传染性。
进行了一项长期随访调查，以研究母亲为HTLV-I血清阳性的婴儿食用冻融母乳后的HTLV-I传染性。
食用冻融母乳的婴儿直到1岁时HTLV-I抗体都未呈阳性，所有随访至11-12岁的儿童抗体均为阴性。
本研究表明，冻融处理可消除母乳中的HTLV-I传染性，HTLV-I携带者可以使用冻融母乳间接喂养婴儿，以此预防HTLV-I感染。
