接受来自I型人类嗜T淋巴细胞病毒阳性母亲的冻融母乳的婴儿的长期血清学结果。
Long-term serological outcome of infants who received frozen-thawed milk from human T-lymphotropic virus type-I positive mothers.
作者信息
Ando Yoshiya, Ekuni Yutaka, Matsumoto Yoshinari, Nakano Shiro, Saito Kensuke, Kakimoto Kazuhiro, Tanigawa Takuo, Kawa Motohiro, Toyama Takenori
机构信息
Wakayama Medical University, Kihoku Hospital, Obstetrics and Gynecology, Wakayama, Japan.
出版信息
J Obstet Gynaecol Res. 2004 Dec;30(6):436-8. doi: 10.1111/j.1447-0756.2004.00227.x.
AIM
Human T-lymphotropic virus type-I (HTLV-I) infection occurs via mothers' milk during feeding. However, freeze-thaw processing can eliminate the infectivity of the mother's milk of HTLV-I carriers.
METHODS
A long-term follow-up survey was conducted to investigate the HTLV-I infectivity of frozen-thawed mothers' milk among infants whose mothers were HTLV-I seropositive.
RESULTS
Infants fed frozen-thawed mothers' milk did not become HTLV-I antibody-positive up until 1 year old, and all children followed up until an age of 11-12 years were antibody negative.
CONCLUSIONS
This study showed that freeze-thaw processing can eliminate the HTLV-I infectivity of mothers' milk, and that HTLV-I carriers can indirectly feed their infants using frozen-thawed mothers' milk as a way to prevent HTLV-I infection.
目的
人类嗜T淋巴细胞病毒I型（HTLV-I）感染可在哺乳期间通过母乳发生。然而，冻融处理可消除HTLV-I携带者母乳的传染性。
方法
进行了一项长期随访调查，以研究母亲为HTLV-I血清阳性的婴儿食用冻融母乳后的HTLV-I传染性。
结果
食用冻融母乳的婴儿直到1岁时HTLV-I抗体都未呈阳性，所有随访至11-12岁的儿童抗体均为阴性。
结论
本研究表明，冻融处理可消除母乳中的HTLV-I传染性，HTLV-I携带者可以使用冻融母乳间接喂养婴儿，以此预防HTLV-I感染。
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