Ando Y, Matsumoto Y, Nakano S, Saito K, Kakimoto K, Tanigawa T, Ekuni Y, Kawa M, Toyama T
Wakayama Medical University, Kihoku Hospital, Obstetrics and Gynecology, Myoji 219, Katsuragi, Ito, Japan.
J Infect. 2003 Jan;46(1):9-11. doi: 10.1053/jinf.2002.1081.
Human T-lymphotropic virus Type-I (HTLV-I) infects children via mother's milk. Infection of Human T-lymphotropic virus Type-I (HTLV-I) was investigated by long-term follow-up surveys of modified milk-fed children. Our observations of modified milk-fed infants revealed that: 1 of 154 (0.6%) at year 1, 5 of 129 (3.9%) at 1.5 years, and 5 of 108 (4.6%) at year 2 were anti-HTLV-I antibody-positive. No infants or children became newly antibody-positive thereafter. Modified milk feeding could prevent the HTLV-I infection of infants from mothers in many cases, however the infants who had became anti-HTLV-I antibody-positive due to established infection by the age 2 remained positive at age 11-12 with persistent infections. Modified milk-fed infants who had been born from HTLV-I seropositive mothers did not show that they had complete protection from HTLV-I infection, but a low infection rate was seen, showing that modified milk feeding is useful to protect from HTLV-I infection.
人类嗜T淋巴细胞病毒I型（HTLV-I）可通过母乳感染儿童。通过对食用改良奶粉儿童的长期随访调查，对人类嗜T淋巴细胞病毒I型（HTLV-I）感染情况进行了研究。我们对食用改良奶粉婴儿的观察结果显示：1岁时154名中有1名（0.6%）、1.5岁时129名中有5名（3.9%）、2岁时108名中有5名（4.6%）抗HTLV-I抗体呈阳性。此后没有婴儿或儿童新出现抗体阳性。在许多情况下，食用改良奶粉可预防婴儿感染来自母亲的HTLV-I，然而，那些在2岁时因已感染而抗HTLV-I抗体呈阳性的婴儿，在11 - 12岁时仍因持续感染而呈阳性。出生于HTLV-I血清阳性母亲的食用改良奶粉婴儿并未显示出对HTLV-I感染有完全的保护作用，但感染率较低，表明食用改良奶粉有助于预防HTLV-I感染。
