使用反相整体柱通过高效液相色谱法快速筛选选定的有机炸药。

Rapid screening of selected organic explosives by high performance liquid chromatography using reversed-phase monolithic columns.

作者信息

Paull Brett, Roux Claude, Dawson Michael, Doble Philip

机构信息

National Centre for Sensor Research, School of Chemical Sciences, Dublin City University, Glasnevin, Dublin 9, Ireland.

出版信息

J Forensic Sci. 2004 Nov;49(6):1181-6.

PMID:15568688

Abstract

This study presents the rapid screening of various high grade explosives by high performance liquid chromatography (HPLC) with monolithic stationary phases. Two gradient methods were developed, the first for quantitative analysis of eleven explosives: HMX; RDX; Tetryl; TNT; 2,3-DNT; 2,6-DNT; 3,4-DNT; 2-NT; 3-NT; 4-NT; and PETN in under 14 min. The second method separated seven explosives in under two min and is suitable for rapid screening to determine the presence of specific and/or class of explosive. The rapid screening methods were successfully applied to soils spiked with known amounts of target explosives. This technology showed excellent potential for forensic explosives detection and analysis.

摘要

本研究介绍了使用整体固定相的高效液相色谱法（HPLC）对各种高级炸药进行快速筛查。开发了两种梯度方法，第一种用于在14分钟内对11种炸药进行定量分析：奥克托今（HMX）、黑索今（RDX）、特屈儿、三硝基甲苯（TNT）、2,3-二硝基甲苯（2,3-DNT）、2,6-二硝基甲苯（2,6-DNT）、3,4-二硝基甲苯（3,4-DNT）、2-硝基甲苯（2-NT）、3-硝基甲苯（3-NT）、4-硝基甲苯（4-NT）和季戊四醇四硝酸酯（PETN）。第二种方法在两分钟内分离出7种炸药，适用于快速筛查以确定特定炸药和/或炸药类别的存在。这些快速筛查方法已成功应用于添加了已知量目标炸药的土壤。该技术在法医炸药检测和分析方面显示出巨大潜力。