Ramella-Roman Jessica C, Lee Ken, Prahl Scott A, Jacques Steven L
Oregon Medical Laser Center, Providence St. Vincent Medical Center, Portland, Oregon, USA.
J Biomed Opt. 2004 Nov-Dec;9(6):1305-10. doi: 10.1117/1.1781667.
Polarized light imaging has been used to detect the borders of skin cancer and facilitate assessment of cancer boundaries. A design for an inexpensive handheld polarized camera is presented and clinical images acquired with this prototype are shown. The camera is built with two universal serial bus (USB) color video cameras, a polarizing beamsplitter cube, and a 4x objective lens. Illumination is provided by three white LEDs and a sheet polarizer. Horizontal and vertical linearly polarized reflected images are processed at 7 frames/s and a resulting polarized image is displayed on screen. We compare the performances of cheap USB camera and a 16-bit electronically cooled camera. Dark noise and image repeatability are compared. In both cases, the 16-bit camera outperforms the USB cameras. Despite these limitations, the results obtained with this USB prototype are very satisfactory. Examples of polarized images of lesions taken prior to surgery are presented.
偏振光成像已被用于检测皮肤癌的边界并有助于评估癌症边界。本文介绍了一种廉价手持偏振相机的设计，并展示了用该原型机获取的临床图像。该相机由两个通用串行总线（USB）彩色视频摄像机、一个偏振分束立方棱镜和一个4倍物镜组成。照明由三个白色发光二极管和一个偏振片提供。水平和垂直线性偏振反射图像以每秒7帧的速度进行处理，并在屏幕上显示生成的偏振图像。我们比较了廉价USB相机和16位电子冷却相机的性能。比较了暗噪声和图像重复性。在这两种情况下，16位相机的性能均优于USB相机。尽管存在这些局限性，但用该USB原型机获得的结果非常令人满意。文中给出了手术前病变的偏振图像示例。
