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综述文章:微量营养素营养不良与幽门螺杆菌感染之间存在关联吗?

Review article: is there a link between micronutrient malnutrition and Helicobacter pylori infection?

作者信息

Salgueiro J, Zubillaga M, Goldman C, Barrado A, Martinez Sarrasague M, Leonardi N, Boccio J

机构信息

Stable Isotope Laboratory Applied to Biology and Medicine, Physics Department, School of Pharmacy and Biochemistry, University of Buenos Aires, Ciudad de Buenos Aires, Argentina.

出版信息

Aliment Pharmacol Ther. 2004 Nov 15;20(10):1029-34. doi: 10.1111/j.1365-2036.2004.02265.x.

Abstract

Helicobacter pylori causes a chronic gastric infection, which is usually life-long. Many epidemiological studies have shown that this is probably one of the most common bacterial infections throughout the world involving 30% of the population living in developed countries and up to 80-90% of the population in developing regions. Concomitantly, developing regions also have high prevalence of micronutrient malnutrition. In the last few years, some studies have suggested that H. pylori infection may affect the homeostasis of different micronutrients including iron, vitamin B12, folic acid, alpha-tocopherol, vitamin C and beta-carotene. In this article, we discuss the current scientific information of the effect that H. pylori infection may produce on micronutrient malnutrition.

摘要

幽门螺杆菌会引发慢性胃部感染,这种感染通常会伴随一生。许多流行病学研究表明,这可能是全球最常见的细菌感染之一,发达国家30%的人口以及发展中地区高达80 - 90%的人口都受其影响。与此同时,发展中地区微量营养素营养不良的患病率也很高。在过去几年里,一些研究表明,幽门螺杆菌感染可能会影响包括铁、维生素B12、叶酸、α - 生育酚、维生素C和β - 胡萝卜素在内的不同微量营养素的体内平衡。在本文中,我们将讨论幽门螺杆菌感染可能对微量营养素营养不良产生影响的当前科学信息。

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