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对南亚裔患者强化糖尿病护理服务的评估:英国亚洲糖尿病研究(UKADS)。

Evaluation of delivery of enhanced diabetes care to patients of South Asian ethnicity: the United Kingdom Asian Diabetes Study (UKADS).

作者信息

O'Hare J P, Raymond N T, Mughal S, Dodd L, Hanif W, Ahmad Y, Mishra K, Jones A, Kumar S, Szczepura A, Hillhouse E W, Barnett A H

机构信息

Biomedical Research Institute, University of Warwick, Coventry, UK.

出版信息

Diabet Med. 2004 Dec;21(12):1357-65. doi: 10.1111/j.1464-5491.2004.01373.x.

Abstract

AIMS

We tested the hypothesis that enhanced care for diabetes, tailored to the needs of the South Asian community with Type 2 diabetes, would improve risk factors for diabetic vascular complications and ultimately reduce morbidity and mortality.

PATIENTS AND METHODS

The study was a cluster randomized controlled trial (RCT) with general practice the unit of randomization. Six West Midlands general practices with a high proportion of South Asian patients were randomized to 'enhanced care' using Asian link workers and extra community diabetes specialist nurse sessions (intervention) or continued standard practice care (control).

RESULTS

Of 401 patients recruited to the study, 361 (90%), comprising 178 from Coventry and 183 from Birmingham were eligible and included in the analyses. The mean age at baseline (standard deviation, SD) was 58.9 (11.7 years) with median (interquartile range; IQR) duration of diabetes 6.5 (3-11) years. At one year follow-up there was a significant difference in reduction of systolic (4.6 mmHg, P = 0.035) and diastolic blood pressure (3.4 mmHg, P = 0.003) and total cholesterol (0.4 mmol/l, P = 0.005), comparing the intervention and control groups. After adjusting for baseline measurement and age, only differential reduction in diastolic blood pressure remained significant. There was no significant change in HbA(1c) and no difference between the groups.

CONCLUSIONS

Using link workers and extra community diabetes specialist nurse input together with treatment protocols in primary care might prove a useful strategy in working towards NSF targets for diabetes management. In this study, small reductions in blood pressure and cholesterol were achieved. Improvement in glycaemic control may require longer and possibly different strategies. Further research is required to evaluate fully the effectiveness, including the costs and longer term sustainability of culturally sensitive initiatives.

摘要

目的

我们检验了这样一个假设,即针对患有2型糖尿病的南亚社区的需求强化糖尿病护理,会改善糖尿病血管并发症的危险因素,并最终降低发病率和死亡率。

患者与方法

该研究是一项整群随机对照试验(RCT),以全科医疗作为随机分组单位。六家西米德兰兹郡的全科医疗诊所,其中南亚裔患者比例较高,被随机分为采用亚洲联络人员和额外社区糖尿病专科护士会诊的“强化护理”组(干预组)或继续接受标准常规护理组(对照组)。

结果

在招募到该研究中的401名患者中,361名(90%)符合条件并纳入分析,其中178名来自考文垂,183名来自伯明翰。基线时的平均年龄(标准差,SD)为58.9岁(11.7岁),糖尿病病程中位数(四分位间距;IQR)为6.5年(3 - 11年)。在一年的随访中,干预组和对照组在收缩压降低(4.6 mmHg,P = 0.035)、舒张压降低(3.4 mmHg,P = 0.003)和总胆固醇降低(0.4 mmol/l,P = 0.005)方面存在显著差异。在对基线测量值和年龄进行调整后,仅舒张压降低差异仍具有统计学意义。糖化血红蛋白(HbA1c)无显著变化,两组之间也无差异。

结论

在初级保健中使用联络人员、额外的社区糖尿病专科护士投入以及治疗方案,可能是朝着糖尿病管理的国家服务框架目标努力的一种有用策略。在本研究中,实现了血压和胆固醇的小幅降低。血糖控制的改善可能需要更长时间且可能不同的策略。需要进一步研究以全面评估其有效性,包括文化敏感举措的成本和长期可持续性。

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